https://pubmed.ncbi.nlm.nih.gov/31856269/
Multiple myeloma with 1q21 amplification is highly sensitive to MCL-1 targeting
Prosurvival BCL-2 family proteins are potent inhibitors of apoptosis and often overexpressed in lymphoid malignancies. In multiple myeloma (MM), MCL-1...
multiple myeloma
https://scholars.lib.ntu.edu.tw/entities/publication/7d59ff39-a183-4334-a61c-59fc94345a86
Linkage analysis of schizophrenia to chromosome 1q21-22 in Taiwanese families
linkageanalysisschizophrenia
https://pubmed.ncbi.nlm.nih.gov/37282609/
Concomitant deletion of the short arm (del(1p13.3)) and amplification or gain (1q21) of chromosome...
The PFS and OS of patients with combined abnormalities of del (1p13.3)/1q21gain or amp was significantly worse compared to del(1p13.3) alone and 1q21gain or...