Robuta

https://www.wikidata.org/wiki/Q34472638 The crystal structure of human Atg4b, a processing and de-conjugating enzyme for... https://pubmed.ncbi.nlm.nih.gov/27527864/ O-GlcNAcylation of ATG4B positively regulates autophagy by increasing its hydroxylase activity Autophagy is a catabolic degradation process and maintains cellular homeostasis. And autophagy is activated in response to various stress conditions. Although... https://pmc.ncbi.nlm.nih.gov/articles/PMC5562857/ A reversible phospho-switch mediated by ULK1 regulates the activity of autophagy protease ATG4B -... Upon induction of autophagy, the ubiquitin-like protein LC3 is conjugated to phosphatidylethanolamine (PE) on the inner and outer membrane of autophagosomes to... https://pubchem.ncbi.nlm.nih.gov/gene/Atg4b/rat Atg4b (Norway rat) | Gene Target - PubChem Gene target information for Atg4b - autophagy related 4B, cysteine peptidase (Norway rat). Find diseases associated with this biological target and compounds... norway ratgenetargetpubchem https://pubmed.ncbi.nlm.nih.gov/28287329/ ATG4B contains a C-terminal LIR motif important for binding and efficient cleavage of mammalian... The cysteine protease ATG4B cleaves off one or more C-terminal residues of the inactive proform of proteins of the ortholog and paralog LC3 and GABARAP... https://profiles.wustl.edu/en/publications/a-novel-atg4b-antagonist-inhibits-autophagy-and-has-a-negative-im/fingerprints/?sortBy=alphabetically A novel ATG4B antagonist inhibits autophagy and has a negative impact on osteosarcoma tumors -...