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https://nij.ojp.gov/library/publications/plasma-pharmacokinetics-and-pharmacodynamic-effects-2-benzylbenzimidazole Plasma pharmacokinetics and pharmacodynamic effects of the 2-benzylbenzimidazole synthetic opioid,... This study investigated the pharmacokinetics of isotonitazene in rats, and related pharmacokinetic parameters to pharmacodynamic effects. of theplasmapharmacokineticseffects