Robuta

https://about.uq.edu.au/experts/project/28574 Development of complement C5aR1 antagonists for the treatment of motor neuron disease | Project |... motor neuron diseasefor the https://pubmed.ncbi.nlm.nih.gov/40072066/?dopt=Abstract Finerenone Alleviates Over-Activation of Complement C5a-C5aR1 Axis of Macrophages by Regulating G... Diabetic nephropathy (DN), one of the most common complications of diabetes mellitus (DM), accounts for a major cause of chronic kidney disease (CKD)... https://www.frontiersin.org/journals/immunology/articles/10.3389/fimmu.2024.1475165/full Frontiers | Disruption of the C5a/C5aR1 axis confers protection against hookworm infection in lung Hookworms are soil-transmitted parasitic nematodes that penetrate the host skin before migrating to the lungs. With an estimated 500-700 million people infec... https://about.uq.edu.au/experts/project/47849 Complement C5aR1: A novel therapeutic target for brain cancer | Project | UQ Experts a noveltherapeutic target https://pubmed.ncbi.nlm.nih.gov/37948857/ C5a/C5aR1 axis as a key driver promotes epithelial-to-mesenchymal transition in airway epithelial... Previous studies have shown that silica nanoparticles (SiNPs) exposure can affect the respiratory, cardiovascular, reproductive and other systems, with the...