https://pubmed.ncbi.nlm.nih.gov/32161196/
Differentiated agonistic antibody targeting CD137 eradicates large tumors without hepatotoxicity
CD137 (4-1BB) is a member of the TNFR superfamily that represents a promising target for cancer immunotherapy. Recent insights into the function of TNFR...
differentiatedantibodytargetinglargetumors
https://clinicaltrials.stanford.edu/trials/f/NCT01114256.html
FNA Tumor Sampling for CD137 Modulation: A Pilot Study
Stanford Health Care delivers the highest levels of care and compassion. SHC treats cancer, heart disease, brain disorders, primary care issues, and many more.
a pilotfnatumorsamplingmodulation
https://digitalcommons.lib.uconn.edu/dissertations/AAI3520424/
"CD134 Plus CD137 Dual Costimulation Induces Eomesodermin in CD4 T Cell" by Harry Z Qui
Cytotoxic CD4 Th1 cells are emerging as a therapeutically useful T cell lineage that can effectively target tumors, but until now the pathways that govern...
https://www.frontiersin.org/journals/immunology/articles/10.3389/fimmu.2018.02618/full
Frontiers | CD137 (4-1BB) Signalosome: Complexity Is a Matter of TRAFs
CD137 (4-1BB, Tnsfr9) is a member of the TNF-receptor (TNFR) superfamily without known intrinsic enzymatic activity in its cytoplasmic domain. Hence, akin to...
is amatter offrontiers
https://pubmed.ncbi.nlm.nih.gov/41379565/
Diabetes exacerbates destructive inflammation by activating the CD137L-CD137 axis in dendritic and...
Periodontal disease, a bacterial infection affecting a large percentage of the world's population, is an important risk factor for several systemic diseases...
https://www.researchandmarkets.com/reports/5768940/cd137-antibodies-clinical-trials-and-market
CD137 Antibodies Clinical Trials & Market Opportunity Insight
clinical trialsmarket opportunityantibodiesinsight
https://muidsi.missouri.edu/enhancing-single-cell-rna-seq-analysis-and-annotation-for-understanding-the-impact-of-cd137-agonist-on-cancer-immunoprevention-through-advanced-informatics-algorithms-2/
Enhancing Single Cell RNA-seq Analysis and Annotation for Understanding the Impact of CD137 Agonist...
SA-4-1BBL, a novel CD137 receptor agonist, has been generated by our group and selected as a promising candidate for preventing cancer progression in research....