https://pubmed.ncbi.nlm.nih.gov/33553777/
Cuprizone markedly decreases kynurenic acid levels in the rodent brain tissue and plasma
This is the first evidence of marked reduction in KYNA levels in a non-immune mediated model of MS. Our results suggest an involvement of the KP in the...
https://tobias-lib.uni-tuebingen.de/xmlui/handle/10900/87431
Combination of cuprizone and experimental autoimmune encephalomyelitis to study inflammatory brain...
to studycombinationexperimental
https://www.frontiersin.org/journals/neurology/articles/10.3389/fneur.2023.989132/full
Frontiers | Inhibiting microglia exacerbates the early effects of cuprizone in males in a rat model...
Hyper-activity of the brain's innate immune cells, microglia, is a hallmark of multiple sclerosis (MS). However, it is not clear whether this involvement of ...
https://www.mdpi.com/2073-4409/9/4/843
The Cuprizone Model: Dos and Do Nots
Multiple sclerosis (MS) is a chronic inflammatory demyelinating disease of the central nervous system. Various pre-clinical models with different specific...
modeldosnots