https://www.frontiersin.org/journals/immunology/articles/10.3389/fimmu.2017.01799/full
Frontiers | CXCR1/2 Antagonism Is Protective during Influenza and Post-Influenza Pneumococcal...
Rationale: Influenza A infections are a leading cause of morbidity and mortality worldwide especially when associated with secondary pneumococcal infections....
frontiersantagonism
https://boris-portal.unibe.ch/entities/publication/acf5fb44-becf-4ef1-b6c4-54d4e6c6cdf4
Cleavage of CXCR1 on neutrophils disables bacterial killing in cystic fibrosis lung disease
Interleukin-8 (IL-8) activates neutrophils via the chemokine receptors CXCR1 and CXCR2. However, the airways of individuals with cystic fibrosis are frequently...
https://pubmed.ncbi.nlm.nih.gov/40993312/
Gemcitabine-induced neutrophil extracellular traps via interleukin-8-CXCR1/2 pathway promote...
Our findings reveal that NETs contribute to chemoresistance in PDAC and that IL-8-mediated chemoNETosis plays a pivotal role in this process. Inhibition of...