https://pubmed.ncbi.nlm.nih.gov/33377972/
Effect of Capivasertib in Patients With an AKT1 E17K-Mutated Tumor: NCI-MATCH Subprotocol EAY131-Y...
ClinicalTrials.gov Identifier: NCT00700882.
https://www.frontiersin.org/journals/cell-and-developmental-biology/articles/10.3389/fcell.2020.573599/full
Frontiers | Effect of AKT1 (p. E17K) Hotspot Mutation on Malignant Tumorigenesis and Prognosis
The substitution of the seventeenth amino acid glutamate by lysine in the homologous structural domain of the Akt1 gene pleckstrin is a somatic cellular muta...