https://scholars.duke.edu/publication/1708186
Scholars@Duke publication: BRCA1-A and LIG4 complexes mediate ecDNA biogenesis and cancer drug...
https://pubmed.ncbi.nlm.nih.gov/39181133/
The Fanconi anemia pathway induces chromothripsis and ecDNA-driven cancer drug resistance
Chromothripsis describes the catastrophic shattering of mis-segregated chromosomes trapped within micronuclei. Although micronuclei accumulate DNA...
fanconi anemia