https://pubmed.ncbi.nlm.nih.gov/15470257/
FKBP12 controls aspartate pathway flux in Saccharomyces cerevisiae to prevent toxic intermediate...
FKBP12 is a conserved member of the prolyl-isomerase enzyme family and serves as the intracellular receptor for FK506 that mediates immunosuppression in...
https://pubmed.ncbi.nlm.nih.gov/10330150/
Rapamycin antifungal action is mediated via conserved complexes with FKBP12 and TOR kinase homologs...
Cryptococcus neoformans is a fungal pathogen that causes meningitis in patients immunocompromised by AIDS, chemotherapy, organ transplantation, or high-dose...
https://www.ncbi.nlm.nih.gov/Structure/pdb/1J4I
1J4I: crystal structure analysis of the FKBP12 complexed with 000308 small molecule
crystal structureof the