https://academicworks.cuny.edu/cc_pubs/44/
"Ubr1 and Ubr2 Function in a Quality Control Pathway for Degradation of" by Nadinath B. Nillegoda,...
Ubr1 and Ubr2 ubiquitin ligases are shown to promote degradation of misfolded cytosolic polypeptides in vivo and in a purified system in association with Hsp70.