https://academicworks.cuny.edu/sph_pubs/115/
"A PLSPM-Based Test Statistic for Detecting Gene-Gene Co-Association in" by Xiaoshuai Zhang,...
For genome-wide association data analysis, two genes in any pathway, two SNPs in the two linked gene regions respectively or in the two linked exons...
https://cran.r-project.org/web/checks/check_results_plspm.html
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https://cran.r-project.org/src/contrib/Archive/plspm/?C=S;O=A
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