https://pubmed.ncbi.nlm.nih.gov/24618832/
Polycystin-1 mediates mechanical strain-induced osteoblastic mechanoresponses via potentiation of...
Mechanical regulation of bone formation involves a complex biophysical process, yet the underlying mechanisms remain poorly understood. Polycystin-1 (PC1) is...
mechanicalstrain
https://pmc.ncbi.nlm.nih.gov/articles/PMC14729/
Polycystin-2, the protein mutated in autosomal dominant polycystic kidney disease (ADPKD), is a...
Defects in polycystin-2, a ubiquitous transmembrane glycoprotein of unknown function, is a major cause of autosomal dominant polycystic kidney disease (ADPKD),...
https://www.ncbi.nlm.nih.gov/protein/5T4D_D
Chain D, hPKD:198-703, Polycystin-2 - Protein - NCBI
chainproteinncbi
https://digitalcommons.chapman.edu/pharmacy_articles/37/
"Loss of Polycystin-1 in Human Cyst-Lining Epithelia Leads to Ciliary D" by Surya M. Nauli, Sandro...
A "two-hit" hypothesis predicts a second somatic hit, in addition to the germline mutation, as a prerequisite to cystogenesis and has been proposed to explain...