Robuta

https://pubmed.ncbi.nlm.nih.gov/36096339/ Cytosolic sequestration of spatacsin by Protein Kinase A and 14-3-3 proteins Mutations in SPG11, encoding spatacsin, constitute the major cause of autosomal recessive Hereditary Spastic Paraplegia (HSP) with thinning of the corpus... protein kinase a