Robuta

https://www.frontiersin.org/journals/oncology/articles/10.3389/fonc.2022.972372/full Frontiers | Discovery of spirooxindole-derived small-molecule compounds as novel HDAC/MDM2 dual... Simultaneous inhibition of more than one target is considered to be a novel strategy in cancer therapy. Owing to the importance of histone deacetylases (HDAC...