https://www.wikidata.org/wiki/Q24310148
Isolation of angiopoietin-1, a ligand for the TIE2 receptor, by secretion-trap expression cloning -...
https://pubmed.ncbi.nlm.nih.gov/12082108/
Deletion of the carboxyl terminus of Tie2 enhances kinase activity, signaling, and function....
Tie2 is an endothelial receptor tyrosine kinase that is required for both embryonic vascular development and tumor angiogenesis. There is considerable interest...
of the
https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0163732
Constitutive Association of Tie1 and Tie2 with Endothelial Integrins is Functionally Modulated by...
Functional cross-talk between Tie2 and Integrin signaling pathways is essential to coordinate endothelial cell adhesion and migration in response to the...
https://pmc.ncbi.nlm.nih.gov/articles/PMC21162/
Antiangiogenic gene therapy targeting the endothelium-specific receptor tyrosine kinase Tie2 - PMC
Angiogenesis is required for tumor growth and metastasis, and inhibition of angiogenesis is a promising approach for anticancer therapy. Tie2 (a.k.a Tek) is an...
gene therapy
https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=409556
CDD Conserved Protein Domain Family: IgI_Tie2
cd20964 (PSSM ID: 409556): Conserved Protein Domain Family IgI_Tie2, The members here are composed of the immunoglobulin (Ig) domain of Tie2 tyrosine kinase
cddproteindomainfamilyigi