https://pubmed.ncbi.nlm.nih.gov/39773557/?dopt=Abstract
Complexes of vertebrate TMC1/2 and CIB2/3 proteins form hair-cell mechanotransduction cation...
Calcium and integrin-binding protein 2 (CIB2) and CIB3 bind to transmembrane channel-like 1 (TMC1) and TMC2, the pore-forming subunits of the inner-ear...
https://pubchem.ncbi.nlm.nih.gov/gene/TMC1
TMC1 | Gene Target - PubChem
Gene target information for TMC1. Find diseases associated with this biological target and compounds tested against it in bioassay experiments.
genetargetpubchem
https://infoscience.epfl.ch/entities/publication/96b90f40-57c7-4ce9-a72d-c77081878139/statistics
Single and Dual Vector Gene Therapy with AAV9-PHP.B Rescues Hearing in Tmc1 Mutant Mice
AAV-mediated gene therapy is a promising approach for treating genetic hearing loss. Replacement or editing of the Tmc1 gene, encoding hair cell mechanosensory...
https://pubchem.ncbi.nlm.nih.gov/gene/Tmc1/rat
Tmc1 (Norway rat) | Gene Target - PubChem
Gene target information for Tmc1 - transmembrane channel-like 1 (Norway rat). Find diseases associated with this biological target and compounds tested against...
norway ratgenetargetpubchem
https://infoscience.epfl.ch/entities/publication/96b90f40-57c7-4ce9-a72d-c77081878139/articledetails
Single and Dual Vector Gene Therapy with AAV9-PHP.B Rescues Hearing in Tmc1 Mutant Mice
AAV-mediated gene therapy is a promising approach for treating genetic hearing loss. Replacement or editing of the Tmc1 gene, encoding hair cell mechanosensory...