https://www.ncbi.nlm.nih.gov/Structure/pdb/2LQ7
2LQ7: E2 binding surface on Uba3 beta-grasp domain undergoes a conformational transition
NEDD8-activating enzyme E1 catalytic subunit
https://pubmed.ncbi.nlm.nih.gov/14690597/
The structure of the APPBP1-UBA3-NEDD8-ATP complex reveals the basis for selective ubiquitin-like...
E1 enzymes initiate ubiquitin-like protein (ubl) transfer cascades by catalyzing adenylation of the ubl's C terminus. An E1's selectivity for its cognate ubl...