Robuta

https://www.ncbi.nlm.nih.gov/Structure/pdb/7K6Q 7K6Q: Active state Dot1 bound to the H4K16ac nucleosome DNA (146-MER)Histone H2A type 1Histone H2B 1.1Histone H3.2Histone H4Histone-lysine N-methyltransferase, H3 lysine-79 specificUbiquitinS-ADENOSYLMETHIONINE to theactivestateboundnucleosome