Robuta

https://pubmed.ncbi.nlm.nih.gov/28368422/ Abl kinase regulation by BRAF/ERK and cooperation with Akt in melanoma The melanoma incidence continues to increase, and the disease remains incurable for many due to its metastatic nature and high rate of therapeutic resistance.... abl kinase https://pubmed.ncbi.nlm.nih.gov/24456693/ BCR-ABL kinase domain mutations, including 2 novel mutations in imatinib resistant Malaysian... Discovery of imatinib mesylate (IM) as the targeted BCR-ABL protein tyrosine kinase inhibitor (TKI) has resulted in its use as the frontline therapy for... abl kinase https://portal.fis.tum.de/en/publications/the-immunogenicity-of-bcr-abl-expressing-dendritic-cells-is-depen/ The immunogenicity of Bcr-Abl-expressing dendritic cells is dependent on the Bcr-Abl kinase... https://www.wikidata.org/wiki/Q28188375 Abl interactor 1 promotes tyrosine 296 phosphorylation of mammalian enabled (Mena) by c-Abl kinase... scientific article (publication date: 13 June 2003) https://pmc.ncbi.nlm.nih.gov/articles/PMC5352070/ Novel Src/Abl tyrosine kinase inhibitor bosutinib suppresses neuroblastoma growth via inhibiting... Neuroblastoma (NB) is the most common extracranial solid tumor in children. Aberrant activation of the non-receptor tyrosine kinases Src and c-Abl contributes... tyrosine kinase https://pubmed.ncbi.nlm.nih.gov/12851468/ Activation and signaling of the Abl tyrosine kinase: bidirectional link with phosphoinositide... Activation and signaling of the Abl tyrosine kinase: bidirectional link with phosphoinositide signaling of the https://www.ncbi.nlm.nih.gov/Structure/pdb/3UE4 3UE4: Structural and spectroscopic analysis of the kinase inhibitor bosutinib binding to the Abl... Tyrosine-protein kinase ABL14-[(2,4-dichloro-5-methoxyphenyl)amino]-6-methoxy-7-[3-(4-methylpiperazin-1-yl)propoxy]quinoline-3-carbonitrile https://www.mdpi.com/1422-0067/21/19/7277 c-Abl Tyrosine Kinase Is Regulated Downstream of the Cytoskeletal Protein Synemin in Head and Neck... The intermediate filament synemin has been previously identified as novel regulator of cancer cell therapy resistance and DNA double strand break (DSB) repair.... https://www.techtransfer.nih.gov/patent/e-147-2010-0-us-01 C-Abl Tyrosine Kinase Inhibitors Useful For Inhibiting Filovirus Replicationc | Technology Transfer tyrosine kinase inhibitors useful for https://www.scirp.org/journal/paperinformation?paperid=38951 Distinct Transforming Activity of ABL Family Tyrosine Kinase Oncogenes Is Induced by Their... Discover the molecular differences between TEL/ARG and TEL/ABL oncogenes in human leukemia. Explore the role of C-termini in regulating growth signals and... https://pubmed.ncbi.nlm.nih.gov/12652307/ A new link between the c-Abl tyrosine kinase and phosphoinositide signalling through PLC-gamma1 The c-Abl tyrosine (Tyr) kinase is activated after platelet-derived-growth factor receptor (PDGFR) stimulation in a manner that is partially dependent on Src... https://pubmed.ncbi.nlm.nih.gov/41162931/ BCR-ABL tyrosine kinase inhibitors associated acute kidney injury: a pharmacovigilance study based... tyrosine kinase inhibitors acute kidney injury https://www.ncbi.nlm.nih.gov/protein/1ABO_A Chain A, ABL TYROSINE KINASE - Protein - NCBI tyrosine kinase chain abl protein ncbi