https://www.ncbi.nlm.nih.gov/Structure/pdb/6TT0
6TT0: Crystal structure of a potent and reversible dual binding site Acetylcholinesterase chiral...
https://impact.ornl.gov/en/publications/open-back-door-in-a-molecular-dynamics-simulation-of-acetylcholin/
Open "back door" in a molecular dynamics simulation of acetylcholinesterase - Oak Ridge National...
molecular dynamics simulation
https://www.ncbi.nlm.nih.gov/Structure/pdb/8AEN
8AEN: Human acetylcholinesterase in complex with zinc and...
Acetylcholinesterase2-acetamido-2-deoxy-beta-D-glucopyranoseCHLORIDE IONMAGNESIUM...
humanacetylcholinesterasecomplexzinc
https://pubmed.ncbi.nlm.nih.gov/29651884/
Kinetic and structural studies on the interactions of Torpedo californica acetylcholinesterase with...
Acetylcholinesterase inhibitors were introduced for the symptomatic treatment of Alzheimer's disease (AD). Among the currently approved inhibitors, donepezil...
structural studieson the
https://scholars.uky.edu/es/publications/acetylcholinesterase-inhibitor-treatment-is-associated-with-relat/
Acetylcholinesterase inhibitor treatment is associated with relatively slow cognitive decline in...
is associated withcognitive declineacetylcholinesteraseinhibitortreatment
https://publications-cnrc.canada.ca/eng/view/object/?id=451935d3-f491-4784-a884-cc8c2478d038
Analysis of human erythrocyte ghosts for acetylcholinesterase, 5'-nucleotidase and superoxide...
Analysis of human erythrocyte ghosts for acetylcholinesterase, 5'-nucleotidase and superoxide dismutase
analysishumanghosts
https://forge.engineering.asu.edu/furiproject/optimizing-cell-culture-methods-for-acetylcholinesterase-production/
Optimizing Cell Culture Methods for Acetylcholinesterase Production - Fulton Forge Student Research...
Apr 16, 2024 - The Clark Lab currently produces Acetylcholinesterase (AChE) for use in pH-responsive nanosensors in-house, by collecting waste media from transfected HEK293T...
cell cultureoptimizingmethods
https://pubmed.ncbi.nlm.nih.gov/26528153/
Developmental role of acetylcholinesterase in impulse control in zebrafish
Cellular and molecular processes that mediate individual variability in impulsivity, a key behavioral component of many neuropsychiatric disorders, are poorly...
impulse controldevelopmentalroleacetylcholinesterasezebrafish
https://www.ncbi.nlm.nih.gov/protein/1QIJ_A
Chain A, ACETYLCHOLINESTERASE - Protein - NCBI
chainacetylcholinesteraseproteinncbi
https://pubmed.ncbi.nlm.nih.gov/34230570/
Acetylcholinesterase and monoamine oxidase-B inhibitory activities by ellagic acid derivatives...
Among 276 herbal extracts, a methanol extract of Castanopsis cuspidata var. sieboldii stems was selected as an experimental source for novel...
monoamine oxidaseellagic acidacetylcholinesteraseb
https://stacks.cdc.gov/view/cdc/40292
Sensitive magnetic nanoparticle-based immunoassay of phosphorylated acetylcholinesterase using...
We developed a new magnetic nanoparticle sandwich-like immunoassay using protein cage nanoparticles (PCN) for signal amplification together with graphite...
sensitivemagneticnanoparticlebasedimmunoassay
https://pmc.ncbi.nlm.nih.gov/articles/PMC21394/
Human endplate acetylcholinesterase deficiency caused by mutations in the collagen-like tail...
In skeletal muscle, acetylcholinesterase (AChE) exists in homomeric globular forms of type T catalytic subunits (ACHET) and heteromeric asymmetric forms...
https://pmr.lf1.cuni.cz/keywords/Acetylcholinesterase-(AChE)/
Keyword Acetylcholinesterase (AChE) | Prague Medical Report
Prague Medical Report is multidisciplinary biomedical journal published quarterly by the First Faculty of Medicine of Charles University in Prague.
keywordacetylcholinesteraseachepraguemedical
https://digital.library.adelaide.edu.au/items/99e1b0e0-5740-4291-b830-3be00d7ba05e
A sensitive approach for screening acetylcholinesterase inhibition of water samples using...
A sensitive assay was developed to evaluate inhibitory effects of aqueous solution on acetylcholinesterase (AChE) activity via measuring hydrolysis rates of...
sensitiveapproachscreening
https://publica.fraunhofer.de/entities/publication/3ca8b54d-cb87-4854-85d0-332e9a89d432
Inhibition of rainbow trout acetylcholinesterase by aqueous and suspended particle-associated...
Spraydrift and edge-of-field runoff are important routes of pesticide entry into streams. Pesticide contamination originating from spraydrift usually resides...
rainbow troutinhibitionacetylcholinesterase
https://experts.umn.edu/en/publications/species-related-differences-in-the-inhibition-of-brain-acetylchol/fingerprints/
Species-related differences in the inhibition of brain acetylcholinesterase by paraoxon and...
species relatedin the
https://www.wikidata.org/wiki/Q39473018
Rapid accumulation of high molecular weight acetylcholinesterase in transected sciatic nerve -...
scientific article published on January 1978
molecular weightrapidaccumulationhigh
https://pubchem.ncbi.nlm.nih.gov/bioassay/1307532
AID 1307532 - Inhibition of electric eel acetylcholinesterase at 1000 uM preincubated for 5 mins...
BioAssay record AID 1307532 submitted by ChEMBL: Inhibition of electric eel acetylcholinesterase at 1000 uM preincubated for 5 mins followed by addition of...
https://www.usgs.gov/publications/some-enzymatic-properties-brain-acetylcholinesterase-bluegill-and-channel-catfish
Some enzymatic properties of brain Acetylcholinesterase from bluegill and channel catfish | U.S....
Using a manometric technique an acetylcholinesterase (EC 3.1.1.7, acetylcholine acetyl-hydrolase) was demonstrated in brain tissue from the bluegill, Lepomis...
https://pubchem.ncbi.nlm.nih.gov/bioassay/1307536
AID 1307536 - Inhibition of human erythrocytes acetylcholinesterase preincubated for 5 mins...
BioAssay record AID 1307536 submitted by ChEMBL: Inhibition of human erythrocytes acetylcholinesterase preincubated for 5 mins followed by addition of...
aidinhibitionhuman
https://pubmed.ncbi.nlm.nih.gov/19190589/
Predicting response to acetylcholinesterase inhibitor treatment in Alzheimer disease: has the time...
Identification of both the initial and the sustained clinical benefits achieved with symptomatic treatments for Alzheimer disease (AD) is a challenge. This...
https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0121092
A Wrench in the Works of Human Acetylcholinesterase: Soman Induced Conformational Changes Revealed...
Irreversible inactivation of human acetylcholinesterase (hAChE) by organophosphorous pesticides (OPs) and chemical weapon agents (CWA) has severe morbidity and...
in the works
https://www.frontiersin.org/journals/molecular-neuroscience/articles/10.3389/fnmol.2012.00036/full
Frontiers | Trans-acting factors governing acetylcholinesterase mRNA metabolism in neurons
The most characterized function of acetylcholinesterase (AChE) is to terminate cholinergic signaling at neuron-neuron and neuro-muscular synapses. In additio...
frontierstransactingfactorsgoverning
https://pubmed.ncbi.nlm.nih.gov/26505950/
Perilla frutescens Extract Ameliorates Acetylcholinesterase and Trimethyltin Chloride-Induced...
One of the critical features of Alzheimer's disease is cognitive dysfunction, which is, in part, due to decreases in acetylcholine (ACh). The ethanol extract...
perilla frutescensextractacetylcholinesterasechlorideinduced
https://pmc.ncbi.nlm.nih.gov/articles/PMC9826304/
Donepezil inhibits neuromuscular junctional acetylcholinesterase and enhances synaptic transmission...
Donepezil, a piperidine inhibitor of acetylcholinesterase (AChE) prescribed for treatment of Alzheimer's disease, has adverse neuromuscular effects in humans,...
donepezilneuromuscularacetylcholinesteraseenhancessynaptic
https://pmc.ncbi.nlm.nih.gov/articles/PMC7483309/
Residential proximity to greenhouse crops and pesticide exposure (via acetylcholinesterase...
Off-target drift of pesticides from farms increases the risk of pesticide exposure of people living nearby. Cholinesterase inhibitors (i.e. organophosphates...
greenhouse cropspesticide exposureresidentialproximityvia
https://www.wikidata.org/wiki/Q49050105
The correlation between choline acetyltransferase and acetylcholinesterase activity in different...
scientific article published in March 1969
correlationcholineacetyltransferaseactivitydifferent
https://www.ncbi.nlm.nih.gov/protein/2HA3_B
Chain B, Acetylcholinesterase - Protein - NCBI
chainbacetylcholinesteraseprotein
https://pubmed.ncbi.nlm.nih.gov/16876707/
Acetylcholinesterase mutation in an insecticide-resistant population of the codling moth Cydia...
Two strains of Cydia pomonella (L.) (Lepidoptera: Tortricidae) were selected in the lab by exposure to increasing concentrations of diflubenzuron (Rdfb strain)...
https://research.birmingham.ac.uk/en/publications/distribution-of-acetylcholinesterase-and-choline-acetyltransferas/
Distribution of acetylcholinesterase and choline-acetyltransferase in guinea-pig heart - University...
guinea pigdistributionacetylcholinesterase
https://researchconnect.buffalo.edu/en/publications/novel-approach-for-the-search-for-chemical-scaffolds-with-dual-ac/
Novel approach for the search for chemical scaffolds with dual activity with acetylcholinesterase...
for thenovelapproachsearch
https://www.mdpi.com/2073-4441/15/4/664
Enhancement of Anticancer, Antibacterial, and Acetylcholinesterase Inhibition Activities from...
The growth response and biological activity of the cyanobacterium Oscillatoria sancta were investigated in starvation conditions. Oscillatoria sancta growth...
enhancementanticancerantibacterialacetylcholinesteraseinhibition
https://pubmed.ncbi.nlm.nih.gov/18408941/
Study of acetylcholinesterase activity in rectal suction biopsy for diagnosis of intestinal...
Although the utility of the acetylcholinesterase (AChE) histochemistry on rectal suction biopsy in diagnosing Hirschsprung's disease (HD) has been documented,...
studyacetylcholinesteraseactivity
https://pubs.rsc.org/en/Content/ArticleLanding/2017/CY/C6CY02473D
Polyhydroxamicalkanoate as a bioinspired acetylcholinesterase-based catalyst for acetylthiocholine...
Acetylcholinesterase (AChE)-based biosensing methods are limited due to facile denaturation and leakage during the immobilization process. Accordingly, enzyme...
as abioinspiredacetylcholinesterasebasedcatalyst
https://www.ncbi.nlm.nih.gov/Structure/pdb/1Q83
1Q83: Crystal structure of the mouse acetylcholinesterase-TZ2PA6 syn complex
crystal structureof themouseacetylcholinesterasesyn
https://www.ncbi.nlm.nih.gov/Structure/pdb/1B41
1B41: HUMAN ACETYLCHOLINESTERASE COMPLEXED WITH FASCICULIN-II, GLYCOSYLATED PROTEIN
ACETYLCHOLINESTERASEFASCICULIN-22-acetamido-2-deoxy-beta-D-glucopyranosealpha-L-fucopyranose
humanacetylcholinesteraseiiprotein
https://pubmed.ncbi.nlm.nih.gov/8240688/
Amniotic fluid acetylcholinesterase is found in gastroschisis but not omphalocele
Amniotic fluid acetylcholinesterase (ACHE) has been used to evaluate neutral tube defects. It has also been detected in ventral wall defects. However, the role...
amniotic fluidacetylcholinesterasefoundgastroschisisomphalocele
https://www.ncbi.nlm.nih.gov/Structure/pdb/4A23
4A23: Mus musculus Acetylcholinesterase in complex with racemic C5685
mus musculusacetylcholinesterasecomplex
https://pubmed.ncbi.nlm.nih.gov/37722189/
BODIPY-labelled acetylcholinesterase reactivators can be encapsulated into ferritin nanovehicles...
The BODIPY-labelled oxime reactivator was prepared and used to study its biodistribution into central nervous system. The newly synthesized oxime was found to...
can belabelledacetylcholinesteraseencapsulatedferritin
https://indianmedicine.eldoc.ub.rug.nl/70609/
Tabernaemontana divaricata extract inhibits neuronal acetylcholinesterase activity in rats - ABIM -...
extractneuronalacetylcholinesteraseactivityrats
https://www.cochrane.org/de/evidence/CD006986_acetylcholinesterase-inhibitor-treatment-myasthenia-gravis
Acetylcholinesterase inhibitor treatment for myasthenia gravis | Cochrane
treatment formyasthenia gravisacetylcholinesteraseinhibitorcochrane
https://researchportal.helsinki.fi/sv/publications/discovery-of-dual-binding-site-acetylcholinesterase-inhibitors-id/
Discovery of Dual Binding Site Acetylcholinesterase Inhibitors Identified by Pharmacophore...
binding sitediscoverydualacetylcholinesteraseinhibitors
https://edoc.ub.uni-muenchen.de/25876/
Reaktivierung Insektizid-gehemmter humaner Acetylcholinesterase durch eine Kombination der Oxime...
reaktivierunginsektizidacetylcholinesterasedurcheine
https://pubmed.ncbi.nlm.nih.gov/19539805/
Effect of acetylcholinesterase oxime-type reactivators K-48 and HI-6 on human liver microsomal...
Substances K-48 and HI-6, oxime-type acetylcholinesterase (AChE) reactivators, were tested for their potential to inhibit the activities of human liver...
https://pubmed.ncbi.nlm.nih.gov/15566295/
Acetylcholinesterase inhibitory activity of scopolin and scopoletin discovered by virtual screening...
For the targeting selection of acetylcholinesterase (AChE) inhibitors from natural sources we generated a structure-based pharmacophore model utilizing an in...
acetylcholinesteraseinhibitoryactivity
https://experts.arizona.edu/en/publications/diagnosis-and-characterization-of-insecticide-insensitive-acetylc/
Diagnosis and characterization of insecticide-insensitive acetylcholinesterase in three populations...
diagnosischaracterizationinsecticideinsensitiveacetylcholinesterase
https://journals.librarypublishing.arizona.edu/lymph/article/id/3192/
A COMPARATIVE STUDY OF ACETYLCHOLINESTERASE ACTIVITY IN BOVINE (S.CERVI) AND HUMAN (B. MALAYI, W....
Setaria cervi, a bovine filarial parasite, contains a significant amount of acetylcholinesterase (AChE) activity with microfilaria having five to ten times...
https://actamedica.lfhk.cuni.cz/60/1/0037/
The Evaluation of Benefit of Newly Prepared Reversible Inhibitors of Acetylcholinesterase and...
Acta Medica is a scientific journal of Charles University in Prague, Faculty of Medicine in Hradec Kralove
the evaluationbenefitnewlypreparedreversible
https://researchconnect.buffalo.edu/en/publications/the-crystal-structure-of-a-complex-of-acetylcholinesterase-with-a/
The crystal structure of a complex of acetylcholinesterase with a bis-(-)-nor-meptazinol derivative...
the crystal
https://pubs.rsc.org/en/Content/ArticleLanding/2026/MD/D6MD00165C
Quinoline/thiazole compounds as selective acetylcholinesterase inhibitors: synthesis and biological...
Acetylcholine (ACh), acetylcholinesterase enzyme (AChE), and AChE inhibition are of great importance in the treatment of neurodegenerative diseases. When it...
thiazolecompoundsselectiveacetylcholinesteraseinhibitors
https://dshb.biology.uiowa.edu/AE-2
Acetylcholinesterase Antibody (AE-2) - DSHB
Catalog FieldsClone ID/Product Name: AE-2Available to For-Profits: YesAlternate Antibody Name: Gene Symbol: Ab Isotype: MIgMGene Name: Antibody Registry ID:...
acetylcholinesteraseantibodyae
https://discovery.fiu.edu/display/pub61155
In vitro oxime protection of human red blood cell acetylcholinesterase inhibited by...
in vitro
https://eprints.soton.ac.uk/423777/
Structure-based optimization of nonquaternary reactivators of acetylcholinesterase inhibited by...
structurebasedoptimizationacetylcholinesteraseinhibited
https://pubmed.ncbi.nlm.nih.gov/18571631/
Novel isosorbide di-ester compounds as inhibitors of acetylcholinesterase
We report herein that a variety of isosorbide di-esters, previously reported to be novel substrates for butyrylcholinesterase (BuChE, EC 3.1.1.8), are in fact...
novelisosorbidediestercompounds