https://pmc.ncbi.nlm.nih.gov/articles/PMC11592889/
Does Incretin Agonism Have Sustainable Efficacy? - PMC
Recent clinical trials using synthetic incretin hormones, glucagon-like peptide 1 (GLP-1), and glucose-dependent insulinotropic polypeptide (GIP) receptor...
sustainableefficacypmc
https://pubchem.ncbi.nlm.nih.gov/bioassay/1804950
AID 1804950 - In Vitro Functional Activity (Agonism) on Human S1P5 Receptors from US Patent...
BioAssay record AID 1804950 submitted by BindingDB: In Vitro Functional Activity (Agonism) on Human S1P5 Receptors from US Patent US10807991:
https://pmc.ncbi.nlm.nih.gov/articles/PMC2948287/
Biased agonism - PMC
Seven-transmembrane receptors are commonly coupled to multiple signaling pathways in cells. The simple model describing agonists for these receptors as...
biasedpmc
https://experts.mcmaster.ca/scholarly-works/210990
Combined mTOR inhibition and OX40 agonism enhances...
Learn about the scholarly work entitled Combined mTOR inhibition and OX40 agonism enhances...
combinedmtorinhibitionenhances
https://pmc.ncbi.nlm.nih.gov/articles/PMC12273586/
How THC works: Explaining ligand affinity for, and partial agonism of, cannabinoid receptor 1 - PMC
Interaction with cannabinoid receptor 1 (CB1) partially determines the bioactivity of the phytocannabinoids. Consequently, there has also been significant...
https://research.monash.edu/en/publications/broad-spectrum-neuroprotection-against-traumatic-brain-injury-by-/
Broad-spectrum neuroprotection against traumatic brain injury by agonism of peroxisome...
traumatic brain injurybroad spectrumneuroprotection
https://www.frontiersin.org/journals/systems-neuroscience/articles/10.3389/fnsys.2021.698240/full
Frontiers | Acute Corticotropin-Releasing Factor Receptor Type 2 Agonism Results in Sustained...
Background: myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a complex multi-symptom disease with widespread evidence of disrupted systems. The...
https://researchdiscovery.drexel.edu/esploro/outputs/doctoral/D3-receptor-agonism-attenuates-deficits-observed/991014632191604721
D3 receptor agonism attenuates deficits observed in rodents with 6-OHDA-induced medial forebrain...
Parkinson's Disease (PD) is a neurodegenerative disorder associated with the progressive loss of dopaminergic neurons in the substantia nigra. This pathology...
https://pmc.ncbi.nlm.nih.gov/articles/PMC10705578/
Physiology of the Weight Loss Plateau after Calorie Restriction, GLP-1 Receptor Agonism, and...
To investigate why different weight loss interventions result in varying durations of weight loss prior to approaching plateaus. A validated mathematical model...
https://events.diabetes.org/p/s/gip-agonism-vs-antagonism-3953
GIP Agonism vs. Antagonism - American Diabetes Association
american diabetesgipvsantagonismassociation
https://boris-portal.unibe.ch/entities/publication/ee866270-4239-45c4-9b18-25a97d2b31af
Correction: GIP receptor agonism improves dyslipidemia and atherosclerosis independently of body...
gip receptorcorrectionimproves
https://pubmed.ncbi.nlm.nih.gov/40301583/
GIPR agonism and antagonism decrease body weight and food intake via different mechanisms in male...
Agonists and antagonists of the glucose-dependent insulinotropic polypeptide receptor (GIPR) enhance body weight loss induced by glucagon-like peptide-1...
https://pubmed.ncbi.nlm.nih.gov/16011657/
Estrogenic agonism and antagonism of the soy isoflavone genistein in uterus, bone and lymphopoiesis...
The isoflavone genistein (Gen) is a naturally occurring phytoestrogen found in high concentrations in soy. The biological effects of Gen have been extensively...
https://www.research.va.gov/about/funded_research/proj-details-FY2023.cfm?pid=582930
I01BX001786-06A1 - PPARgamma agonism in lung immune response
lungimmuneresponse
https://www.mdpi.com/2073-4409/9/1/37
Anti-NASH Drug Development Hitches a Lift on PPAR Agonism
Non-alcoholic fatty liver disease (NAFLD) affects one-third of the population worldwide, of which a substantial number of patients suffer from non-alcoholic...
drug developmentantinashhitcheslift
https://www.southampton.ac.uk/research/projects/developing-immunostimulatory-antibodies-to-deliver-agonism-without-toxicity
Developing immunostimulatory antibodies to deliver agonism without toxicity | University of...
Developing immunostimulatory antibodies to deliver agonism without toxicity.
developingantibodiesdeliverwithouttoxicity
https://researchconnect.buffalo.edu/en/publications/targeting-pro-dopaminergic-agonism-to-attenuate-and-depression-in/
Targeting pro-dopaminergic agonism to attenuate and depression in patient's displaying...
https://events.diabetes.org/p/s/what-does-glucagon-receptor-agonism-add-to-the-effects-of-gip-and-glp-1-receptor-agonism-5584
What Does Glucagon Receptor Agonism Add to the Effects of GIP and GLP-1 Receptor Agonism? -...
https://research.monash.edu/en/publications/new-paradigms-in-adenosine-receptor-pharmacology-allostery-oligom/
New paradigms in adenosine receptor pharmacology: allostery, oligomerization and biased agonism -...
adenosine receptornewparadigms