Robuta

https://pmc.ncbi.nlm.nih.gov/articles/PMC6275946/ The Allosteric Site on SHP2’s Protein Tyrosine Phosphatase Domain is Targetable with Druglike Small... Difficulties in developing active-site-directed protein tyrosine phosphatase (PTP) inhibitors have led to the perception that PTPs are “undruggable”,... protein tyrosine phosphataseallosteric sitedomaintargetabledruglike