Robuta

https://adisinsight.springer.com/drugsafety/803496275?error=cookies_not_supported&code=a03918d2-f5aa-4807-b120-fe847b5404c3 Antineoplastics - AdisInsight A woman in her late 50s developed pancytopenia during treatment with dexamethasone, vincristine, daunorubicin and pegaspargase for acute leukemia. The woman had antineoplasticsadisinsight https://adisinsight.springer.com/drugsafety/801042390?error=cookies_not_supported&code=d9eb54e8-c402-41a9-b9c2-c027c60ce834 Antineoplastics/dexamethasone/pegfilgrastim - AdisInsight Adjuvant antineoplastic therapy for breast cancer with pegfilgrastim support was associated with leucocytosis in one woman and febrile neutropenia in two other antineoplasticsdexamethasonepegfilgrastimadisinsight https://adisinsight.springer.com/drugsafety/803612017?error=cookies_not_supported&code=e454f180-5b62-46d4-b4a1-4f71fa9d251b Antineoplastics/glucocorticoids - AdisInsight A 54-year-old man experienced inefficacy during treatment with hydrocortisone and methylprednisolone for human T-cell leukaemia virus type 1 (HTLV-1)-associated antineoplasticsglucocorticoidsadisinsight https://adisinsight.springer.com/drugsafety/803764065?error=cookies_not_supported&code=2f7711f8-55fc-49a1-ab7c-6daa95286059 Antineoplastics - AdisInsight In an observational retrospective study, a 67-year-old man was described who developed panniculitis, myalgia and mild pneumonitis during treatment with antineoplasticsadisinsight https://adisinsight.springer.com/drugsafety/803555422?error=cookies_not_supported&code=93cd991b-3c29-4352-be81-84b35056c62d Antineoplastics - AdisInsight A 60-year-old man developed an increase in total bilirubin (T-Bil) during treatment with ponatinib, cyclophosphamide, vincristine, doxorubicin and dexamethasone antineoplasticsadisinsight https://adisinsight.springer.com/drugsafety/803126998?error=cookies_not_supported&code=5cbb64ac-72c7-4766-8b71-c0ff8107fd84 Antineoplastics - AdisInsight Details of this case report have previously been published [see Reactions 1429 p9; [1] ]. antineoplasticsadisinsight https://adisinsight.springer.com/drugsafety/803681757?error=cookies_not_supported&code=52bc9450-da15-4901-b830-198144433622 Antineoplastics - AdisInsight A 6-month-old male patient exhibited lack of efficacy during treatment with cyclophosphamide, dactinomycin, doxorubicin, ifosfamide and vincristine for antineoplasticsadisinsight https://adisinsight.springer.com/drugsafety/803413693?error=cookies_not_supported&code=e0be3fb1-93c8-41c7-855a-339696597c11 Antineoplastics - AdisInsight A 60-year-old woman developed leucopenia, neutropenia, anaemia and pyrogenic neutropenia during treatment with chemotherapy, comprising bevacizumab, antineoplasticsadisinsight https://adisinsight.springer.com/drugsafety/803387472?error=cookies_not_supported&code=65d7e5ad-a025-4416-b9a1-25c5271eff00 Antineoplastics - AdisInsight In a retrospective bi-centric study of 48 patients treated between January 2012 and May 2018 for brain metastases, three patients were described [ages and sexes antineoplasticsadisinsight https://adisinsight.springer.com/drugsafety/803925904?error=cookies_not_supported&code=8213626f-0f7f-4bb8-b128-18018908641e Antineoplastics - AdisInsight Ten patients [ages and sexes not stated] with haematological malignancies developed severe neutropenia and thrombocytopenia during treatment with chemotherapy antineoplasticsadisinsight https://adisinsight.springer.com/drugsafety/803566665?error=cookies_not_supported&code=720afaf0-e780-4a30-ba4d-fe943a847c1d Antineoplastics - AdisInsight A 62-year-old woman exhibited lack of efficacy with fluorouracil, gemcitabine, oxaliplatin and paclitaxel while being treated for undifferentiated carcinoma antineoplasticsadisinsight https://adisinsight.springer.com/drugsafety/803419676?error=cookies_not_supported&code=172cbb15-62f0-4ed0-93c3-69d10686116f Antineoplastics - AdisInsight An adult woman [exact age at the time of reaction onset not stated] developed intensifying pain in the extremities, mandible pain secondary to imatinib, antineoplasticsadisinsight https://adisinsight.springer.com/drugsafety/803685193?error=cookies_not_supported&code=757c4501-dc7d-4a8e-98a4-9c817bbf5e17 Antineoplastics - AdisInsight A 9-year-old boy developed chemotherapy toxicities in the form of mucositis, nausea, vomiting, febrile neutropenia and myelosuppression during treatment with antineoplasticsadisinsight https://adisinsight.springer.com/drugsafety/803607405?error=cookies_not_supported&code=dd10ccb5-7c97-4a23-b8a1-f8c7eb4016f8 Antineoplastics - AdisInsight An 18-month-old male infant exhibited treatment failure during treatment with dexamethasone and clofarabine for histiocytic sarcoma (HS) with BRAFV600E mutation antineoplasticsadisinsight https://adisinsight.springer.com/drugsafety/800503534?error=cookies_not_supported&code=3069343e-3860-4316-a0cf-6650cb32f79b Antineoplastics - AdisInsight The association between induction chemotherapy of non-Hodgkin's lymphoma and the development of pulmonary embolus has been reported previously antineoplasticsadisinsight https://adisinsight.springer.com/drugsafety/803761466?error=cookies_not_supported&code=d5aec897-a13c-471e-ae69-ef7fcdcabbf6 Antineoplastics/micafungin - AdisInsight A 58-year-old woman developed febrile neutropenia and disseminated bullous candidiasis due to Candida tropicalis infection during chemotherapy with idarubicin, antineoplasticsmicafunginadisinsight https://adisinsight.springer.com/drugsafety/803322795?error=cookies_not_supported&code=e2261c0c-1a61-4b28-8b3a-849a18dcb75f Antineoplastics - AdisInsight A 16-year-old boy developed oral mucositis, Raoultella planticola infection and febrile neutropenia during treatment with vincristine, methotrexate, ifosfamide, antineoplasticsadisinsight https://adisinsight.springer.com/drugsafety/803472168?error=cookies_not_supported&code=dc160788-fa17-420a-9c6a-c95befa25731 Antineoplastics - AdisInsight A 61-year-old man developed myelosuppression and pneumonia during treatment with tucidinostat, prednisone, cyclophosphamide and thalidomide for monomorphic antineoplasticsadisinsight https://adisinsight.springer.com/drugsafety/803096352?error=cookies_not_supported&code=08636073-b7d8-41ec-9428-210486664f11 Antineoplastics/oxycodone/paracetamol - AdisInsight A 43-year-old man developed recurrent Clostridium difficile infection during treatment with vinblastine, bleomycin, dacarbazine, doxorubicin and antineoplasticsoxycodoneparacetamoladisinsight https://adisinsight.springer.com/drugsafety/803924092?error=cookies_not_supported&code=15c8de13-0d01-4896-8962-6cfa7b070560 Antineoplastics - AdisInsight A patient with T-prolymphocytic leukaemia received multi-agent chemotherapy [*age, sex, dosage, route, duration of treatment to reaction onset not stated*] and antineoplasticsadisinsight https://adisinsight.springer.com/drugsafety/803904085?error=cookies_not_supported&code=f7c10634-4c94-446e-9e87-6abc4b3633a9 Antineoplastics - AdisInsight In a retrospective study of 22 patients with biliary tract carcinoma treated between July 2021 and October 2023, 2 patients [ages and sexes not stated] were antineoplasticsadisinsight https://adisinsight.springer.com/drugsafety/803803678?error=cookies_not_supported&code=76c1d299-8fbc-450d-8502-e35acd83489b Antineoplastics - AdisInsight A girl [age at the time of reaction onset not stated] exhibited lack of efficacy while receiving carboplatin, cyclophosphamide, doxorubicin, etoposide and antineoplasticsadisinsight https://adisinsight.springer.com/drugsafety/803587565?error=cookies_not_supported&code=bfb7755c-2cd3-42df-a8f8-e94d34ea115b Antineoplastics - AdisInsight A 66-year-old man exhibited no response during treatment with bortezomib, cisplatin, cyclophosphamide, dexamethasone, etoposide, lenalidomide and ibrutinib for antineoplasticsadisinsight https://adisinsight.springer.com/drugsafety/803928317?error=cookies_not_supported&code=500ea646-cf2c-4f99-a7dd-92104dae518e Antineoplastics - AdisInsight Among 286 patients with lymphoma receiving high-dose chemotherapy followed by autologous stem cell transplantation, 11 experienced treatment-induced pneumonitis antineoplasticsadisinsight https://adisinsight.springer.com/drugsafety/803564122?error=cookies_not_supported&code=f198337f-c0b9-4349-9e36-cb2e7dcac6db Antineoplastics - AdisInsight A 40-year-old woman received off-label treatment with methotrexate and exhibited no response during off-label treatment with cyclophosphamide, doxorubicin, antineoplasticsadisinsight https://adisinsight.springer.com/drugsafety/803018649?error=cookies_not_supported&code=213ede3d-10cf-4c32-bb14-2eb2515e9f62 Antineoplastics - AdisInsight During chemotherapy for choriocarcinoma, a 25-year-old woman developed leucopenia [time to reaction onset not stated], which contributed to the development of antineoplasticsadisinsight https://adisinsight.springer.com/drugsafety/803713206?error=cookies_not_supported&code=4e612b76-0ed8-4c6c-b896-eee3f218517a Antineoplastics - AdisInsight A 42-year-old woman developed rash, oedema of the bilateral ankles and eyelids, knee pain, hyperhidrosis and anaemia during treatment with paclitaxel, antineoplasticsadisinsight https://adisinsight.springer.com/drugsafety/803421597?error=cookies_not_supported&code=25ca21f8-a8e4-4d59-9bb6-2abf63ca657d Antineoplastics/antibiotics - AdisInsight A 21-year-old man developed disseminated invasive aspergillosis (disseminated to intestine and lung) following treatment with rituximab, dexamethasone, antineoplasticsantibioticsadisinsight https://adisinsight.springer.com/drugsafety/803926590?error=cookies_not_supported&code=73493758-b90c-48aa-878b-8f3058fe5597 Antineoplastics - AdisInsight A 61-year-old woman with sigmoid colon adenocarcinoma developed extensive bilobar liver metastases that were initially unresectable. She experienced multiple antineoplasticsadisinsight https://adisinsight.springer.com/drugsafety/803924790?error=cookies_not_supported&code=10cca0f1-e9d1-4039-a308-5ff28fcc4b68 Antineoplastics - AdisInsight A 60-year-old man with refractory diffuse large B-cell lymphoma developed rapidly progressive varicella zoster virus (VZV) vasculopathy while receiving antineoplasticsadisinsight https://adisinsight.springer.com/drugsafety/803585591?error=cookies_not_supported&code=157cb326-d8bd-47f8-a65c-02f9a636856c Antineoplastics - AdisInsight In a study comprising 10 patients treated for locally advanced unresectable pancreatic cancer between November 2017 and February 2019, an approximately antineoplasticsadisinsight https://adisinsight.springer.com/drugsafety/803624059?error=cookies_not_supported&code=beba13eb-c7c7-4359-9259-0b39b301092a Antineoplastics - AdisInsight A 76-year-old woman developed anaemia, thrombocytopenia, leucopenia and transient increase in cytokines during treatment with lenalidomide or tislelizumab for antineoplasticsadisinsight https://adisinsight.springer.com/drugsafety/800412084?error=cookies_not_supported&code=843be281-1735-4a40-90d8-c4926e580a1f Antineoplastics - AdisInsight Six patients developed Clostridium difficile colitis after receiving antineoplastic therapy [dosages not stated] for various malignancies; 3 had underlying GI antineoplasticsadisinsight https://adisinsight.springer.com/drugsafety/803177540?error=cookies_not_supported&code=dc61c2b7-9227-47a5-a111-3fb267e63a14 Antineoplastics - AdisInsight A 66-year-old woman developed neutropenia complicated by sepsis due to Bacteroides fragilis group and Candida grabrata following treatment with antineoplasticsadisinsight https://adisinsight.springer.com/drugsafety/803116861?error=cookies_not_supported&code=fe81abf9-7310-4816-9487-29e3010b98ac Antineoplastics - AdisInsight A 41-year-old woman developed myelopathy with sensory loss, paraparesis and ataxia while receiving busulfan, cyclophosphamide, methotrexate, cytarabine and antineoplasticsadisinsight https://adisinsight.springer.com/drugsafety/803111727?error=cookies_not_supported&code=dec8c60e-bb38-4c68-9dd5-24c5d9a75325 Antineoplastics - AdisInsight One patient [age and sex not stated] died due to drug toxicity during treatment with cyclic BEACOPP antineoplastic chemotherapy regimen included bleomycin, antineoplasticsadisinsight https://adisinsight.springer.com/drugsafety/803855910?error=cookies_not_supported&code=53f216a2-ea5b-4780-8540-9167244116bd Antineoplastics - AdisInsight A female patient [exact age not stated] exhibited no response during treatment with docetaxel, trastuzumab, trastuzumab-emtansine and pertuzumab for metastatic antineoplasticsadisinsight https://adisinsight.springer.com/drugsafety/801118897?error=cookies_not_supported&code=4ccc92b3-c3df-4128-8549-ae0474d2f44f Adalimumab/antineoplastics - AdisInsight A 44-year-old woman who had undergone breast cancer therapy, including chemotherapy, developed acute myeloid leukaemia during treatment with adalimumab [Humira] adalimumabantineoplasticsadisinsight https://adisinsight.springer.com/drugsafety/803896744?error=cookies_not_supported&code=25497bd8-10ce-4045-801e-daef045336c4 Antineoplastics - AdisInsight In a single-arm, retrospective, cohort study of 31 patients, conducted between February 2020 and December 2023, a patient [sex and age not stated] was antineoplasticsadisinsight https://adisinsight.springer.com/drugsafety/801150041?error=cookies_not_supported&code=77ee6841-8f1e-4f5b-b2fa-4db449f342ea Antineoplastics - AdisInsight A 9-year-old girl developed reversible posterior leukoencephalopathy syndrome during the induction phase of treatment with asparaginase, vincristine, antineoplasticsadisinsight https://adisinsight.springer.com/drugsafety/801117723?error=cookies_not_supported&code=fffc1596-0b5c-4681-aa98-d87274201d62 Antineoplastics - AdisInsight Three men developed stomatitis during treatment with S-1 and cisplatin (patients 1 and 2), and S-1 and irinotecan (patient 3); in patient 1, stomatitis worsened antineoplasticsadisinsight https://adisinsight.springer.com/drugsafety/803069259?error=cookies_not_supported&code=9ae31594-7393-4a0c-a616-e419b281ebb1 Antineoplastics - AdisInsight A 32-year-old man developed neutropenia followed by aspergillosis during treatment with antineoplastics.The man was hospitalised for suspected lymphoma relapse, antineoplasticsadisinsight https://adisinsight.springer.com/drugsafety/801158157?error=cookies_not_supported&code=c67e390c-58a7-4b07-a288-31de09047a8a Antineoplastics - AdisInsight A 66-year-old woman developed pathological fractures while receiving chemotherapy according to the R-CHOP regimen (rituximab, cyclophosphamide, vincristine and antineoplasticsadisinsight https://adisinsight.springer.com/drugsafety/803926058?error=cookies_not_supported&code=1b87b9f1-f76b-4e6f-b061-c4d1912933a4 Antineoplastics - AdisInsight Sixty-one patients with Wilms tumour received chemotherapy [antineoplastics; *dosage, age, sex, route not stated*] as part of National Wilms Tumor Study antineoplasticsadisinsight https://adisinsight.springer.com/drugsafety/803572452?error=cookies_not_supported&code=b7cf0ac9-431a-41ec-afe1-d45f9b8ac904 Antineoplastics - AdisInsight A 29-year-old man developed secondary malignant neoplasm in form of the colorectal adenocarcinoma of the sigmoid colon following treatment with antineoplasticsadisinsight https://adisinsight.springer.com/drugsafety/803054004?error=cookies_not_supported&code=44b4ded5-4549-4a33-9b6d-aa44a56e367a Antineoplastics - AdisInsight Two patients, who were hepatitis B virus (HBV) carriers, developed reactivation of HBV following chemotherapy [routes and dosages not stated]; one patient antineoplasticsadisinsight https://adisinsight.springer.com/drugsafety/803796907?error=cookies_not_supported&code=15fdf973-4d23-4a30-8444-76fd7be82953 Antineoplastics/calcium-channel-antagonists - AdisInsight In a retrospective study involving 122 patients with EGFR-mutated non-small cell lung cancer (NSCLC) and treated between January 2015 and December 2020, 23 calcium channelantineoplasticsantagonistsadisinsight https://adisinsight.springer.com/drugsafety/803258374?error=cookies_not_supported&code=9e59231b-f0db-4367-b69e-8b052a379216 Antineoplastics - AdisInsight A 58-year-old man developed thrombocytopenia and peripheral neuropathy [time to reactions onsets and outcomes not stated] while receiving treatment with folinic antineoplasticsadisinsight https://adisinsight.springer.com/drugsafety/803405114?error=cookies_not_supported&code=b039d86d-3382-4bd8-bc38-01d84ac40da3 Antineoplastics - AdisInsight A 63-year-old man developed mild myelosuppression while receiving chemotherapy with cyclophosphamide, doxorubicin [hydroxydaunorubicin], prednisone, vincristine antineoplasticsadisinsight https://adisinsight.springer.com/drugsafety/803080406?error=cookies_not_supported&code=9bc11fe9-f966-475f-9cfb-d9819097ca78 Antineoplastics - AdisInsight An 85-year-old man developed oral mucositis and anorexia while receiving cisplatin, gimeracil/oteracil/tegafur [S-1] and docetaxel.The man, who had gastric antineoplasticsadisinsight https://adisinsight.springer.com/drugsafety/803825543?error=cookies_not_supported&code=00702002-16c1-43a2-bf5a-b7c02631c9eb Antineoplastics - AdisInsight A 44-year-old woman exhibited treatment failure during treatment with pazopanib, ivosidenib, guadecitabine, aplitabart and belinostat for chondrosarcoma [not antineoplasticsadisinsight https://adisinsight.springer.com/drugsafety/803352294?error=cookies_not_supported&code=a6cbd6d2-56f7-4acd-9665-9727dc3be1b3 Antineoplastics - AdisInsight In a study, two children [sexes and specific ages not stated] were described, who developed Aeromonas hydrophila and Aeromonas veronii be sobria infections antineoplasticsadisinsight https://adisinsight.springer.com/drugsafety/803284386?error=cookies_not_supported&code=907688dc-f638-492b-a0de-2873be9c4e21 Antineoplastics - AdisInsight A woman [exact age at the time of reaction onset not stated] developed significant diabetic neuropathy and significant diabetic retinopathy leading to antineoplasticsadisinsight https://adisinsight.springer.com/drugsafety/803295303?error=cookies_not_supported&code=7ce15f4f-e592-4e7a-a078-a305132164c6 Antineoplastics - AdisInsight A woman in her 40s developed nausea, vomiting and fatigue due to etoposide, methylprednisolone, cisplatin and cytarabine; renal dysfunction due to cisplatin; antineoplasticsadisinsight https://adisinsight.springer.com/drugsafety/803716758?error=cookies_not_supported&code=00472903-bf2e-4f93-ae96-46d9d14a3565 Antineoplastics - AdisInsight A 61-year-old woman exhibited lack-of-efficacy during treatment with paclitaxel, carboplatin, bevacizumab and doxorubicin-liposomal for primary peritoneal antineoplasticsadisinsight https://adisinsight.springer.com/drugsafety/807207963?error=cookies_not_supported&code=e3cdd1f6-702f-42a3-9ffe-746a4365fbc5 Antineoplastics/immunosuppressants - AdisInsight antineoplasticsimmunosuppressantsadisinsight https://adisinsight.springer.com/drugsafety/803114295?error=cookies_not_supported&code=62bbd014-50ec-41a8-a88e-d5a4056e86ee Antineoplastics - AdisInsight A patient [sex and age not stated] with soft tissue sarcoma developed renal dysfunction while receiving chemotherapy with the CYVADIC regimen, consisting of antineoplasticsadisinsight https://adisinsight.springer.com/drugsafety/803100753?error=cookies_not_supported&code=78d86fe2-8c13-4422-991a-b66202f9026a Antineoplastics - AdisInsight Two elderly men experienced adverse effects, and subsequently died, while receiving gimeracil/oteracil/tegafur [S1]; the formulation was suspected of playing a antineoplasticsadisinsight