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肝硬化导致血小板减少的因素较多，其中主要原因是“脾功能亢进”—增大的脾脏像一个“过滤器”，把血液里的血小板过度破坏掉了；同时，受损肝脏合成促血小板生成素不足，骨髓制造血小板能力下降，双重作用下血小板持续走低。大约有15%～30%的肝硬化患者
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