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https://www.sintef.no/en/publications/publication/1580721/
Heterologous expression of actinobacterial biosynthetic gene clusters and identification of novel...
biosynthetic gene clusters
heterologous expression
identification
https://pubmed.ncbi.nlm.nih.gov/31612915/
MIBiG 2.0: a repository for biosynthetic gene clusters of known function
Fueled by the explosion of (meta)genomic data, genome mining of specialized metabolites has become a major technology for drug discovery and studying...
biosynthetic gene clusters
repository
https://pubmed.ncbi.nlm.nih.gov/32493747/
Active and repressed biosynthetic gene clusters have spatially distinct chromosome states
While colocalization within a bacterial operon enables coexpression of the constituent genes, the mechanistic logic of clustering of nonhomologous...
biosynthetic gene clusters
active
repressed
distinct
chromosome