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https://pmc.ncbi.nlm.nih.gov/articles/PMC5039522/ Biotin Protein Ligase Is a Target for New Antibacterials - PMC There is a desperate need for novel antibiotic classes to combat the rise of drug resistant pathogenic bacteria, such as Staphylococcus aureus. Inhibitors of... biotin protein ligasefor newtargetantibacterialspmc https://www.ncbi.nlm.nih.gov/Structure/pdb/1X01 1X01: Crystal Structure Of Biotin Protein Ligase From Pyrococcus Horikoshii Ot3 in complex with ATP biotin--[acetyl-CoA-carboxylase] ligaseACETIC ACIDADENOSINE-5'-TRIPHOSPHATEPHOSPHATE ION