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AID 1799422 - Btk Kinase Assay from Article 10.1038/nchembio.481: "Specific Btk inhibition...
BioAssay record AID 1799422 submitted by BindingDB: Btk Kinase Assay from Article 10.1038/nchembio.481:
https://pubmed.ncbi.nlm.nih.gov/22279054/
The clinically active BTK inhibitor PCI-32765 targets B-cell receptor- and chemokine-controlled...
Small-molecule drugs that target the B-cell antigen receptor (BCR) signalosome show clinical efficacy in the treatment of B-cell non-Hodgkin lymphoma. These...
https://pubmed.ncbi.nlm.nih.gov/24954503/
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https://pubmed.ncbi.nlm.nih.gov/23709115/
Inhibition of Btk with CC-292 provides early pharmacodynamic assessment of activity in mice and...
Targeted therapies that suppress B cell receptor (BCR) signaling have emerged as promising agents in autoimmune disease and B cell malignancies. Bruton's...
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https://pubchem.ncbi.nlm.nih.gov/bioassay/1920147
AID 1920147 - IC50 value on BTK wt/C481S Kinase Inhibition from US Patent US20240002387: "METHOD...
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https://pubchem.ncbi.nlm.nih.gov/bioassay/1795100
AID 1795100 - Bruton's Tyrosine Kinase (BTK) Inhibition Assay from US Patent US9556147: "Inhibitors...
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BTK drives neutrophil activation for sterilizing antifungal immunity
We describe a previously unappreciated role for Bruton's tyrosine kinase (BTK) in fungal immune surveillance against aspergillosis, an unforeseen complication...
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LPS-induced vein endothelial cell injury and acute lung injury have Btk and Orai 1 to regulate...
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An Open-label, Phase 1b/2, Safety and Efficacy Study of the Bruton's Tyrosine Kinase (Btk)...
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Bruton's Tyrosine Kinase (BTK) and Vav1 Contribute to Dectin1-Dependent Phagocytosis of Candida...
Author Summary The opportunistic yeast Candida albicans is a commensal organism of the human digestive tract, but also the most common cause of human fungal...
https://pubchem.ncbi.nlm.nih.gov/bioassay/1078753
AID 1078753 - Inhibition of human full length BTK expressed in baculovirus assessed as substrate...
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https://pubmed.ncbi.nlm.nih.gov/27564106/
Preclinical investigation of ibrutinib, a Bruton's kinase tyrosine (Btk) inhibitor, in suppressing...
Standard interventions for glioma include surgery, radiation and chemotherapies but the prognosis for malignant cases such as glioblastoma multiforme remain...
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