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https://www.cancerresearchuk.org/about-cancer/tests-and-scans/transperineal-biopsy Transperineal biopsy for prostate cancer | Tests and scans | Cancer Research UK Your doctor might take small samples of tissue from your prostate. They put a needle into the prostate through the skin behind the testicles (perineum). This... cancer tests and scanstransperineal biopsyprostateresearchuk