Robuta

https://pubmed.ncbi.nlm.nih.gov/34715055/ Reprogramming CBX8-PRC1 function with a positive allosteric modulator Canonical targeting of Polycomb repressive complex 1 (PRC1) to repress developmental genes is mediated by cell-type-specific, paralogous chromobox (CBX)... with areprogrammingfunctionpositiveallosteric