https://blog.innovabiotech.com/blog/allosteric-site-identification
Validate 3–5 Allosteric Sites: Reproducible Pipeline for R&D Teams
Sep 24, 2026 - A reproducible pipeline that combines pocket detection, ML scoring, and MD validation to prioritize and validate top 3–5 allosteric sites.
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https://usiena-air.unisi.it/handle/11365/1220777
Synthesis of Unsymmetrical Squaramides as Allosteric GSK-3β Inhibitors Promoting β-Catenin-Mediated...
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https://pubchem.ncbi.nlm.nih.gov/bioassay/624471
AID 624471 - Beta-Arrestin HTS for Positive Allosteric Modulators of the Human D2 Dopamine...
BioAssay record AID 624471 submitted by National Center for Advancing Translational Sciences (NCATS): Beta-Arrestin HTS for Positive Allosteric Modulators of...
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https://www.frontiersin.org/journals/pharmacology/articles/10.3389/fphar.2020.00914/full
Frontiers | Allosteric Coupling Between Drug Binding and the Aromatic Cassette in the Pore Domain...
Human-ether-a-go-go-related channel (hERG1) is the pore-forming domain of the delayed rectifier K+ channel in the heart which underlies the IKr current. The ...
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https://www.innovations-report.com/science-tech/technology-offerings/allosteric-activators-inhibitors-proteinkinases-agc-132894/
Allosteric Regulation of AGC and Aurora Protein Kinases - Innovations Report
May 19, 2009 - Another new approach to influence protein kinases which is also part of this invention is the allosteric regulation of such enzymes. A hydrophobe binding...
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https://lens.elifesciences.org/32766/
A dynamic mechanism for allosteric activation of Aurora kinase A by activation loop phosphorylation...
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https://paperium.net/article/en/24459/orthosteric-and-allosteric-inhibition-of-the-brain-v-atpase-outside-thealternating-access-cycle
Orthosteric and allosteric inhibition of the brain V-ATPase outside the alternating-access cycle:...
Quick breakdown of the 'Orthosteric and allosteric inhibition of the brain V-ATPase outside the alternating-access cycle' paper. Methods, results, str
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https://lab.vanderbilt.edu/niswender-lab/publication/discovery-of-thieno32-pyridine-5-carboxamide-and-23-difluorobenzamide-negative-allosteric-modulators-of-metabotropic-glutamate-receptor-subtype-5/
Discovery of Thieno[3,2-]pyridine-5-carboxamide and 2,3-Difluorobenzamide Negative Allosteric...
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https://publires.unicatt.it/it/publications/can-a-positive-allosteric-modulation-of-gabaergic-receptors-impro-8/
Can a Positive Allosteric Modulation of GABAergic Receptors Improve Motor Symptoms in Patients with...
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https://par.nsf.gov/biblio/10710822-ae-pocketminer-uses-attention-simultaneously-predict-cryptic-pockets-allosteric-coupling
AE-PocketMiner Uses Attention to Simultaneously Predict Cryptic Pockets and Their Allosteric...
This page contains metadata information for the record with PAR ID 10710822
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https://researchconnect.stonybrook.edu/en/publications/allosteric-regulation-and-inhibition-of-protein-kinases/
Allosteric regulation and inhibition of protein kinases - Stony Brook University
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https://cris.biu.ac.il/en/publications/allosteric-modulation-of-protein-kinase-a-in-individuals-affected/
Allosteric modulation of protein kinase A in individuals affected by NLPD-PKA, a neurodegenerative...
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https://researchconnect.stonybrook.edu/en/publications/ftmove-a-web-server-for-detection-and-analysis-of-cryptic-and-all/
FTMove: A Web Server for Detection and Analysis of Cryptic and Allosteric Binding Sites by Mapping...
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https://knowledge.uchicago.edu/records/1q16q-aw409
Vestigialization of an Allosteric Switch: Genetic and Structural Mechanisms for the Evolution of...
An important goal in molecular evolution is to understand the genetic and physical mechanisms by which protein functions evolve and, in turn, to characterize...
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https://www.jci.org/articles/view/87526/figure/7
JCI - M1 muscarinic allosteric modulators slow prion neurodegeneration and restore memory loss
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https://research.unite.it/handle/11575/98574
In silico mapping of allosteric ligand binding sites in type-1 cannabinoid receptor
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https://www.domaintherapeutics.com/domain-therapeutics-to-present-latest-data-on-dt-9045-a-first-in-class-negative-allosteric-modulator-of-par2-for-immuno-oncology-at-aacr-2024-annual-meeting-highlighting-clear-competitive-advanta/
Domain Therapeutics to present latest data on DT-9045, a first-in-class Negative Allosteric...
May 12, 2025 - DT-9045 is a game-changer in immuno-oncology with competitive pharmacological properties and unique therapeutic potential to unlock new cancer treatment...
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https://mitomycin-c.com/index.php?g=Wap&m=Article&a=detail&id=413
Allosteric PDK4 Inhibitors: Novel Scaffold for Metabolic Dis – Inhibitor Research Hub
Allosteric PDK4 Inhibitors: Novel Scaffold for Metabolic Diseases Study Background and Research Question The regulation of cellular energy metabolis
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https://researchportal.lih.lu/en/publications/biased-antagonism-of-a-series-of-bicyclic-cxcr2-intracellular-all/
Biased antagonism of a series of bicyclic CXCR2 intracellular allosteric modulators - Luxembourg...
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https://nio9.com/general-knowledge/allosteric-effects-section-1/3/
Allosteric Effects - Section 1 NIO9
11. The specificity of a ligand binding site on a protein is based on A. the absence of…
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https://research.itu.edu.tr/en/studentTheses/predicting-potential-allosteric-communication-pathways-in-pyruvat/
Predicting potential allosteric communication pathways in pyruvate kinase using residue network...
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https://lens.elifesciences.org/90773/
Dynamic allosteric networks drive adenosine A1 receptor activation and G-protein coupling | eLife...
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