Robuta

The immune cells that are trained to fight off the body's invaders can become defective. It's what allows cancer to develop. So most research has targeted...

Early-stage NSCLC (stages I and II, and some IIIA diseases) accounts for approximately 30% of non-small cell lung cancer (NSCLC) cases, with surgery being its...

Mesothelioma is a highly malignant condition arising from the pleura and peritoneum that is closely related to asbestos exposure. The prognosis for this...

One of the most interesting and promising areas of medical research today involves the use of T-Cell therapies, which offer hope and promise as a new...

In the last decades, the therapeutic decision-making approach to metastatic renal cell cancer (mRCC) has dramatically changed thanks to the introduction in t...

International center specializing in cancer immunotherapy and stem cell therapy. Personalized protocols using oncolytic viruses, ATACK therapy, and advanced...

Cell therapy offers the potential for curative treatment of cancers. Although T cells have been the predominantly used cell type, natural killer (NK) cells...

Dendritic Cell Therapy IMMUMEDIC LLC: modern network of immunological therapy, combination therapies, and individual treatment options explained in an...

Learn about our world-class doctors for immunotherapy and cell transplants, including bone marrow/stem cell transplants and CAR T-cell therapy.

DNAM-1 is a major NK cell activating receptor and, together with NKG2D and NCRs, by binding specific ligands, strongly contributes to mediating the killing of...

Disease recurrence following chemotherapy and allogeneic hematopoietic cell transplantation is the major unmet clinical need of acute leukemia. Adoptive cell...

This research was supported by internal academic funds and by grants from the Burroughs Wellcome Fund, Sidney Kimmel Foundation, Cancer Research Institute, and...

Cutaneous squamous cell carcinoma (CSCC) accounts for approximately 20% of all keratinocytic tumors. In most cases, the diagnosis and treatments are made on ...

Scientists have demonstrated that personalizing CAR-T cell stimulation during manufacturing can significantly enhance the consistency and potency of the...

T cells are a type of immune cell that finds and kills unhealthy or invading cells such as cancer cells. These T cells find cancer cells by attaching to a...

Discover how bi-specific T cell engagers offer simpler, safer, and more effective cancer immunotherapy, with potential beyond oncology.

Activation and maintenance of the T cell response occurs concurrently with metabolic reprogramming. This ensures the T cell response is supported by sufficient...

Testicular Cancer is the most common type of cancer in teenage and young adult men. Most cases correspond to testicular germ cell tumors (TGCTs). Testicular...

Immunotherapy is a promising new form of cancer treatment, but the supercharged immune cells it employs can become exhausted in the fight. Researchers in Japan...

A new study led by researchers at the Johns Hopkins Kimmel Cancer Center found that patients with advanced basal cell carcinoma (BCC) may benefit from...

The University of Birmingham has launched a trial that could lead to a ground-breaking new way of treating people with two types of chronic liver disease.

This is an open-label single center Phase 1a/1b study with the primary objective of establishing the safety and exploring the efficacy of infusing the ex vivo...

Aug 10, 2025 - In recent decades, immunotherapy has undergone extensive developments for oncologic therapy applications. Dendritic cells (DCs) plays a fundamental role in...

California Institute of Technology

Despite the recent availability of immune checkpoint inhibitors, not all patients affected by Non-Small Cell Lung Cancer (NSCLC) benefit from immunotherapy....

Combination immune checkpoint blockade has demonstrated promising benefit in lung cancer, but predictors of response to combination therapy are unknown. Using...

Adult T-cell leukemia/lymphoma is caused by infection with HTLV-1, following a long latent period. Immunotherapy targeting Aurora kinase A, a tumor-associated...

Cancer is one of the main reasons of death worldwide and its heterogeneity limits the effectiveness of different therapeutic modules. The emergence of cancer...