https://www.frontiersin.org/journals/neurology/articles/10.3389/fneur.2024.1471287/full
Frontiers | The cGAS-STING pathway in ischemia-reperfusion injury in acute cerebral infarction: a...
The innate immune response is the body's first line of defense against external pathogens and endogenous damage signals. The cGAS-STING pathway is a crucial ...
cgas sting pathwayischemia reperfusion injury
https://www.frontiersin.org/journals/pharmacology/articles/10.3389/fphar.2025.1597443/full
Frontiers | Targeting the cGAS-STING pathway: emerging strategies and challenges for the treatment...
The cGAS-STING signaling pathway is a major component of innate immunity. It is critical for identifying cytoplasmic DNA, triggering immune responses, and is...
cgas sting pathway
https://pmc.ncbi.nlm.nih.gov/articles/PMC7151642/
The cytosolic DNA-sensing cGAS-STING pathway in cancer - PMC
The recognition of DNA as an immune stimulatory molecule is an evolutionarily conserved mechanism to initiate rapid innate immune response against microbial...
cgas sting pathwaycytosolicdnasensingcancer
https://www.frontiersin.org/journals/immunology/articles/10.3389/fimmu.2023.1139595/full
Frontiers | Crosstalk between cGAS-STING pathway and autophagy in cancer immunity
The cyclic GMP-AMP synthase-stimulator of interferon genes (cGAS-STING) pathway is critical in cancer immunity. Autophagy is a highly conserved process that ...
cgas sting pathwayfrontierscrosstalk
https://www.mdpi.com/2072-6694/15/1/221
Activation of cGAS-STING Pathway Is Associated with MSI-H Stage IV Colorectal Cancer
Colorectal cancer is the second most common cause of cancer-related mortality in adults. Understanding colorectal tumorigenesis at both the cellular and...
https://www.frontiersin.org/journals/immunology/articles/10.3389/fimmu.2024.1510628/full
Frontiers | Progress of cGAS-STING signaling pathway-based modulation of immune response by...
The cGAS-STING signaling pathway is a critical component of the innate immune response, playing a significant role in various diseases. As a central element ...
signaling pathway
https://www.frontiersin.org/journals/pharmacology/articles/10.3389/fphar.2025.1519429/full
Frontiers | Editorial: Activation of the cGAS-STING pathway by extra-nuclear DNA and its...
potentially contributing to abnormal autoimmune responses (1). Significant efforts are underway to discover specific and effective cGAS-STING inhibitors as r...