dna damage - Robuta Search

https://pubmed.ncbi.nlm.nih.gov/20444606/?dopt=Abstract DNA damage and decisions: CtIP coordinates DNA repair and cell cycle checkpoints Maintenance of genome stability depends on efficient, accurate repair of DNA damage. DNA double-strand breaks (DSBs) are among the most lethal types of DNA... dna damage cell cycle decisions ctip coordinates https://www.news-medical.net/whitepaper/20190308/DNA-Damage-Repair-and-the-Progression-of-the-Cell-Cycle.aspx DNA Damage Repair and the Progression of the Cell Cycle May 13, 2020 - In cancerous cells, many proteins and genes are mutated or overexposed, which can affect and influence the progression of the cell cycle. dna damage repair and the progression cell cycle https://www.sciencedaily.com/releases/2006/08/060803170408.htm Links Between DNA Damage And Breast Cancer Studied | ScienceDaily Researchers from the Pacific Northwest Research Institute and NIST have uncovered a pattern of DNA damage in connective tissues in the human breast that could... dna damage breast cancer links studied sciencedaily https://news.mit.edu/2020/cancer-researchers-collaborate-target-pathways-for-cancer-therapies-1001 Cancer researchers collaborate, target DNA damage repair pathways for cancer therapy | MIT News |... MIT researchers find that blocking the expressions of the genes XPA and MK2 enhances the tumor-shrinking effects of platinum-based chemotherapies in... dna damage repair https://eprints.ncl.ac.uk/248331 Targeting DNA Damage Response Pathways in Cancer - ePrints - Newcastle University dna damage response targeting pathways cancer eprints https://pubmed.ncbi.nlm.nih.gov/34108479/ Activation of PARP2/ARTD2 by DNA damage induces conformational changes relieving enzyme... Human PARP2/ARTD2 is an ADP-ribosyltransferase which, when activated by 5'-phosphorylated DNA ends, catalyses poly-ADP-ribosylation of itself, other proteins... dna damage https://pubmed.ncbi.nlm.nih.gov/11525387/?dopt=Abstract Cisplatin: from DNA damage to cancer chemotherapy Cisplatin [cis-DDP, cis-diamminedichloroplatinum(II)] is a potent anticancer drug that has been used successfully to treat tumors of the head, neck, lungs, and... dna damage cisplatin cancer chemotherapy https://pubmed.ncbi.nlm.nih.gov/29723708/ Broad spectrum detection of DNA damage by Repair Assisted Damage Detection (RADD) Environmental exposures, reactive by-products of cellular metabolism, and spontaneous deamination events result in a spectrum of DNA adducts that if... broad spectrum dna damage detection repair assisted https://health.economictimes.indiatimes.com/news/diagnostics/both-smokers-and-vapers-suffer-similar-dna-damage-study/97916944 Both, smokers and vapers, suffer similar DNA damage: Study, ETHealthworld DNA Damage: E-cigarettes, used regularly by more than 10 per cent of US teens and more than 3 per cent of adults, were once pitched as a healthy alternative to... dna damage smokers vapers suffer similar https://www.ncbi.nlm.nih.gov/gene?term=115265 DDIT4L DNA damage inducible transcript 4 like [Homo sapiens (human)] - Gene - NCBI dna damage https://repository.tudelft.nl/record/uuid:f911518f-389f-4689-ae0e-716c5f6e3b4e Simulation of DNA damage using Geant4-DNA | TU Delft Repository dna damage tu delft simulation using repository https://scholars.uky.edu/es/publications/selective-removal-of-transcription-blocking-dna-damage-from-the-t/ Selective removal of transcription-blocking DNA damage from the transcribed strand of the mammalian... dna damage https://ja.dh.duke.edu/radiation-oncology-imaging-program-roip-seminar-series/content/pharmacology-dna-damage-signaling-immune-system Pharmacology of DNA damage signaling in the immune system | DUKEHealth JA the immune system dna damage pharmacology signaling https://pubmed.ncbi.nlm.nih.gov/33380174/ Electronic Cigarettes Induce Mitochondrial DNA Damage and Trigger TLR9 (Toll-Like Receptor... E-cig increases level of damaged mitochondrial DNA in circulating blood and induces the expression of TLR9, which elevate the expression of proinflammatory... electronic cigarettes mitochondrial dna https://www.sciencedaily.com/releases/2015/07/150722144634.htm DNA damage seen in patients undergoing CT scanning, study finds | ScienceDaily Using new laboratory technology, scientists have shown that cellular damage is detectable in patients after CT scanning. In this study, researchers examined... dna damage seen in ct scanning study finds patients https://www.encyclopedia.com/education/encyclopedias-almanacs-transcripts-and-maps/theories-biological-aging-dna-damage Theories of Biological Aging: DNA Damage | Encyclopedia.com THEORIES OF BIOLOGICAL AGING: DNA DAMAGE The idea that DNA damage may be a major factor in aging has been popular since 1974, when Ronald Hart and Richard... biological aging dna damage theories encyclopedia https://kuscholarworks.ku.edu/entities/publication/abdfbc92-2478-4a2b-82d2-5c706ec23248 Opioid induces increased DNA damage in prefrontal cortex and nucleus accumbens Opioid use disorder (OUD) is a chronic disease characterized by compulsive opioid taking and seeking, affecting millions of people worldwide. The high relapse... dna damage prefrontal cortex opioid increased https://eprints.ncl.ac.uk/250834 Imaging the DNA damage response with PET and SPECT - ePrints - Newcastle University dna damage response with pet https://www.thermofisher.com/antibody/primary/panther/DNA%20damage%20induced%20protein%20phosphorylation DNA damage induced protein phosphorylation Antibodies | Invitrogen Antibodies for proteins involved in DNA damage induced protein phosphorylation pathways, according to their Panther/Gene Ontology Classification dna damage protein phosphorylation induced antibodies invitrogen https://pubchem.ncbi.nlm.nih.gov/protein/Q2HZD6 Growth arrest and DNA-damage-inducible protein 45 alpha (chicken) | Protein Target - PubChem Protein target information for Growth arrest and DNA-damage-inducible protein 45 alpha (chicken). Find diseases associated with this biological target and... dna damage https://wp0.vanderbilt.edu/youngscientistjournal/article/quantifying-reactive-oxidant-induced-dna-damage-through-opda-adducts Quantifying Reactive Oxidant-Induced DNA Damage Through OPdA Adducts | Young Scientist Journal |... Quantifying Reactive Oxidant-Induced DNA Damage Through OPdA Adducts. dna damage https://vivo.colorado.edu/display/meshid_G05.200.104 DNA Damage - DNA Adducts | CU Experts | CU Boulder dna damage cu experts boulder https://pubmed.ncbi.nlm.nih.gov/25371178/ The impact of SF3B1 mutations in CLL on the DNA-damage response Mutations or deletions in TP53 or ATM are well-known determinants of poor prognosis in chronic lymphocytic leukemia (CLL), but only account for approximately... the impact dna damage mutations https://eprints.ncl.ac.uk/153223 DNA damage foci in mitosis are devoid of 53BP1 - ePrints - Newcastle University dna damage https://open.library.emory.edu/concern/publications/fd21003b-f442-4d90-9300-9029580629ac Medulloblastoma and the DNA Damage Response | OpenEmory Medulloblastoma and the DNA Damage Response dna damage response and the medulloblastoma https://pmc.ncbi.nlm.nih.gov/articles/PMC5403131/ Sirtuins and DNA damage repair: SIRT7 comes to play - PMC Aging is characterized by a cumulative loss of genome integrity, which involves chromatin reorganization, transcriptional dysregulation and the accumulation of... dna damage repair to play sirtuins comes pmc https://research.birmingham.ac.uk/en/publications/a-novel-dna-damage-recognition-protein-in-schizosaccharomyces-pom/ A novel DNA damage recognition protein in Schizosaccharomyces pombe - University of Birmingham a novel dna damage https://pubmed.ncbi.nlm.nih.gov/28297716/ RNA m6A methylation regulates the ultraviolet-induced DNA damage response Cell proliferation and survival require the faithful maintenance and propagation of genetic information, which are threatened by the ubiquitous sources of DNA... the ultraviolet dna damage rna methylation induced https://pubmed.ncbi.nlm.nih.gov/15246424/ Linking tumor suppression, DNA damage and the anaphase-promoting complex A recent study shows that the RASSF1A tumor suppressor functions as a regulator of the ordered proteolytic steps that organize mitosis. By controlling the... dna damage and the linking tumor suppression https://pubmed.ncbi.nlm.nih.gov/35881546/?dopt=Abstract Targeting the DNA Damage Response Pathways and Replication Stress in Colorectal Cancer In conclusion, a subset of colorectal cancers refractory to current therapies could benefit from inhibitors of DDR pathways and replication stress. A composite... dna damage response https://pubmed.ncbi.nlm.nih.gov/29959348/?dopt=Abstract Increased nuclear DNA damage precedes mitochondrial dysfunction in peripheral blood mononuclear... Huntington's disease (HD) is a progressive neurodegenerative disorder primarily affecting the basal ganglia and is caused by expanded CAG repeats in the... dna damage mitochondrial dysfunction peripheral blood increased nuclear https://www.ncbi.nlm.nih.gov/protein/GBC11138.1 p53 and DNA damage-regulated protein 1 [Rhizophagus irregularis DAOM 1 - Protein - NCBI dna damage regulated https://www.thermofisher.com/antibody/primary/panther/telomere%20maintenance%20in%20response%20to%20DNA%20damage telomere maintenance in response to DNA damage Antibodies | Invitrogen Antibodies for proteins involved in telomere maintenance in response to DNA damage pathways, according to their Panther/Gene Ontology Classification in response dna damage telomere maintenance antibodies https://pubmed.ncbi.nlm.nih.gov/27076112/ Sperm DNA damage-the effect of stress and everyday life factors The clinical significance of sperm DNA damage lies in its association with natural conception rates and also might have a serious consequence on developmental... dna damage the effect everyday life sperm https://dukespace.lib.duke.edu/items/7b87edca-c5ab-497d-8aef-818e5e8783a1 Fate of Transcription Elongation Complexes Stalled by DNA Damage and Elongation Inhibitors dna damage fate transcription elongation complexes https://publikationen.bibliothek.kit.edu/1000030889 No differences in DNA damage and antioxidant capacity between ... dna damage differences antioxidant capacity https://pure.psu.edu/en/publications/why-is-dna-damage-signaling-so-complicated-chaos-and-molecular-si/ Why is DNA damage signaling so complicated? Chaos and molecular signaling - Penn State dna damage https://pubmed.ncbi.nlm.nih.gov/19847258/?dopt=Abstract The DNA-damage response in human biology and disease The prime objective for every life form is to deliver its genetic material, intact and unchanged, to the next generation. This must be achieved despite... dna damage response in human biology disease https://researchdiscovery.drexel.edu/esploro/outputs/graduate/Hyperglycemic-conditions-may-promote-senescence/991021874814404721 Hyperglycemic conditions may promote senescence & DNA damage in TIMELESS-depleted human cardiac... Increased senescence is a major hallmark of aging and is induced by DNA damage. Senescent cells have undergone irreversible cell cycle arrest and cease to... dna damage https://liu.diva-portal.org/smash/record.jsf?pid=diva2:1062625 Expression of DNA damage response proteins and complete remission after radiotherapy of stage... dna damage response https://biblio.ugent.be/publication/01HKX41V1RT27BSY6S4BJ5KTWJ ALK signaling primes the DNA damage response sensitizing ALK-driven neuroblastoma to therapeutic... dna damage response https://www.sciencedaily.com/releases/2010/12/101202141910.htm Scientists map changes in genetic networks caused by DNA damage | ScienceDaily Using a new technology called "differential epistasis maps," scientists have documented for the first time how a cellular genetic network completely rewires... dna damage scientists map changes genetic https://www.mdpi.com/1422-0067/17/5/748 DNA Damage: A Main Determinant of Vascular Aging Vascular aging plays a central role in health problems and mortality in older people. Apart from the impact of several classical cardiovascular risk factors on... dna damage main determinant vascular aging https://pubmed.ncbi.nlm.nih.gov/28860276/ DNA damage-induced immune response: Micronuclei provide key platform DNA damage-induced activation of the cytoplasmic DNA sensor cGAS influences the outcome of infections, autoinflammation, and cancer. Recent studies by Harding... dna damage immune response induced provide key https://pubmed.ncbi.nlm.nih.gov/20679395/ Apoptosis of leukocytes triggered by acute DNA damage promotes lymphoma formation Apoptosis triggered by p53 upon DNA damage secures removal of cells with compromised genomes, and is thought to prevent tumorigenesis. In contrast, we provide... dna damage apoptosis leukocytes triggered https://liu.diva-portal.org/smash/record.jsf?pid=diva2:1236462 UHRF2 promotes DNA damage response by decreasing p21 via RING finger domain dna damage response https://microbiology.weill.cornell.edu/dna-damage-response-signaling-cascade-regulates-proliferation-phytopathogenic-fungus-ustilago-maydis The DNA damage response signaling cascade regulates proliferation of the phytopathogenic fungus... dna damage response signaling https://pubmed.ncbi.nlm.nih.gov/12832285/?dopt=Abstract Oxidative DNA damage: mechanisms, mutation, and disease Oxidative DNA damage is an inevitable consequence of cellular metabolism, with a propensity for increased levels following toxic insult. Although more than 20... dna damage mechanisms mutation disease https://dspace.rpi.edu/items/768a960c-d3fe-4fe5-9318-994bba4ed519 Investigating the relationship between DNA damage and hormesis in saccharomyces cerevisiae... In addition, a preliminary analysis of expression levels of DNA damage response genes found that they were upregulated during normal aging, but exposure to an... the relationship dna damage investigating https://www.news-medical.net/news/20200616/Persistent-DNA-damage-in-the-placenta-can-affect-embryonic-growth.aspx Persistent DNA damage in the placenta can affect embryonic growth Jun 16, 2020 - Scientists at the Stowers Institute for Medical Research have shown that a dysfunctional placenta can play a previously unrecognized role during the earliest... dna damage in the persistent placenta affect https://pmc.ncbi.nlm.nih.gov/articles/PMC11557828/ Nuclear IMPDH2 controls the DNA damage response by modulating PARP1 activity - PMC Nuclear metabolism and DNA damage response are intertwined processes, but the precise molecular links remain elusive. Here, we explore this crosstalk using... dna damage response https://nucleicacids.sciencezoplanet.com/ Nucleic Acids 2026 | CRISPR 2026 Conference | RNA 2026 | DNA Damage & Repair Conference 2026 |... Apr 15, 2026 - Sciencezo Planet Conferences cordially assembling global biochemists, nucleic acid experts, molecular biology researchers to discuss innovative techniques of... nucleic acids dna damage crispr conference rna https://www.ncbi.nlm.nih.gov/protein/2MRO_B Chain B, DNA damage-inducible protein 1 - Protein - NCBI dna damage chain b protein https://edoc.ub.uni-muenchen.de/3195/ Investigation of UVC Induced DNA Damage Formation and Photolyase Catalyzed Repair of Cyclobutane... dna damage https://www.qatar.cmu.edu/project-tags/dna-damage-repair/ DNA Damage Repair - Carnegie Mellon University in Qatar dna damage repair carnegie mellon university qatar https://www.nist.gov/publications/advances-dna-damage-and-repair Advances in DNA Damage and Repair | NIST dna damage advances repair nist https://medicine.yale.edu/event/dna-damge-and-genome-integrity-2/ DNA Damage and Genome Integrity Research Program Seminar | Yale School of Medicine 04/13/2026 event : If you would like to attend via zoom, please use the link below. Please see flyer for passcode. https://yale.zoom dna damage research program https://pubmed.ncbi.nlm.nih.gov/17616978/ RETRACTED: DNA damage, homology-directed repair, and DNA methylation To explore the link between DNA damage and gene silencing, we induced a DNA double-strand break in the genome of Hela or mouse embryonic stem (ES) cells using... dna damage retracted homology directed repair https://www.rochester.edu/newscenter/study-identifies-key-factor-in-dna-damage-associated-with-aging-222862/ Study identifies key factor in DNA damage associated with aging Mar 24, 2017 - There are many examples of DNA damage being associated with aging, but never has a reduction in DNA damage been shown to extend lifespan. Rochester research... dna damage associated with study identifies key https://pubmed.ncbi.nlm.nih.gov/9020199/ Oxidative liver DNA damage in rats treated with pesticide mixtures Oxidative damage was quantified in the liver of rats by measuring the levels of 8-OH-2-deoxyguanosine (8-OH-2DG) relative to 2-deoxyguanosine in DNA after... dna damage liver rats treated pesticide https://dbbs.wustl.edu/tag/dna-damage-response/ DNA damage response Archives - Division of Biology & Biomedical Sciences dna damage response archives division biology biomedical sciences https://news.drgator.ufl.edu/tag/dna-damage/ DNA damage - Doctor Gator dna damage doctor gator https://eprints.ncl.ac.uk/203001 Guanidine-reactive agent phenylglyoxal induces DNA damage and cancer cell death - ePrints -... dna damage and cancer https://www.thermofisher.com/antibody/primary/panther/regulation%20of%20DNA%20damage%20checkpoint regulation of DNA damage checkpoint Antibodies | Invitrogen Antibodies for proteins involved in regulation of DNA damage checkpoint pathways, according to their Panther/Gene Ontology Classification dna damage regulation checkpoint antibodies invitrogen https://pubmed.ncbi.nlm.nih.gov/11588897/ Kiwifruit protects against oxidative DNA damage in human cells and in vitro Antioxidant micronutrients may account for the beneficial effects of fruits on human health. A direct demonstration that consumption of fruit decreases... dna damage in human kiwifruit protects https://agris.fao.org/search/en/providers/122535/records/65dec00b0f3e94b9e5d0eded Paraquat induced DNA damage by reactive oxygen species dna damage paraquat induced reactive oxygen https://pubmed.ncbi.nlm.nih.gov/25582089/ Petroselinum crispum has antioxidant properties, protects against DNA damage and inhibits... Petroselinum crispum has health-promoting properties with the potential to prevent oxidative stress-related diseases and can be developed into functional food. petroselinum crispum antioxidant properties dna damage https://www.chemie.uni-hamburg.de/en/institute/oc/arbeitsgruppen/meier/forschung/oligos.html DNA Damage by Aromatic Amines : Department of Chemistry : University of Hamburg department of chemistry dna damage aromatic amines university hamburg https://groups.google.com/g/omeganews/c/hQclQGxyXzY DNA Damage From Magnetic Fields Linked To Iron In Cells dna damage magnetic fields linked iron cells https://podcasts.ox.ac.uk/index.php/repairing-dna-damage-0 Repairing DNA damage | University of Oxford Podcasts GENOME INTEGRITY Whilst controlled DNA breaks allow for our vast repertoire of antibodies, DNA damage happening out of context can lead to cancer or... university of oxford dna damage repairing podcasts https://pubmed.ncbi.nlm.nih.gov/19812404/ DNA damage, aging, and cancer DNA damage, aging, and cancer dna damage aging cancer https://cordis.europa.eu/project/id/101030945 Substrate Selectivity in the Ubiquitin-Dependent Response to DNA Damage | DDRDegronDiscovery |... Weak and transient protein-protein interactions are essential for cellular homeostasis but are challenging to study and therefore incompletely understood. Many... in the dna damage substrate selectivity ubiquitin https://pmc.ncbi.nlm.nih.gov/articles/PMC6031472/ Roles of UVA Radiation and DNA Damage Responses in Melanoma Pathogenesis - PMC The growing incidence of melanoma is a serious public health issue that merits a thorough understanding of potential causative risk factors, which includes... dna damage https://takecontrol.substack.com/p/vaping-causes-dna-damage Vaping Causes More DNA Damage Than Regular Cigarettes A 2023 study demonstrated that vaping triggers more DNA damage in the mouth than traditional cigarettes. Read the findings here. dna damage vaping causes regular cigarettes https://pmc.ncbi.nlm.nih.gov/articles/PMC10220248/ DNA damage repair proteins across the Tree of Life - PMC Genome maintenance is orchestrated by a highly regulated DNA damage response with specific DNA repair pathways. Here, we investigate the phylogenetic diversity... the tree of life dna damage repair proteins across pmc https://www.wikidata.org/wiki/Q34328184 Regulation of DNA Damage Responses by Ubiquitin and SUMO - Wikidata scientific article published on February 14, 2013 dna damage regulation responses ubiquitin sumo https://pubmed.ncbi.nlm.nih.gov/21478441/ The DNA damage response signaling cascade regulates proliferation of the phytopathogenic fungus... In the phytopathogenic fungus Ustilago maydis, the dikaryotic state dominates the period of growth occurring during the infectious phase. Dikaryons are cells... dna damage response signaling https://cordis.europa.eu/project/id/850405/reporting/es Dissecting the chromatin response to DNA damage in silenced heterochromatin regions | H2020 |... Latest report summary dna damage https://pubmed.ncbi.nlm.nih.gov/38569820/ Cardiomyocyte DNA Damage Predicts Functional Recovery in Heart Failure Patients Cardiomyocyte DNA Damage Predicts Functional Recovery in Heart Failure Patients dna damage functional recovery heart failure cardiomyocyte predicts https://eprints.ncl.ac.uk/205482 Chapter 14, Monitoring DNA Damage During Cell Senescence - ePrints - Newcastle University dna damage cell senescence chapter monitoring https://cordis.europa.eu/project/id/850405/results/es Dissecting the chromatin response to DNA damage in silenced heterochromatin regions | CHROMREP |... Deliverables, publications, datasets, software, exploitable results dna damage https://tagteam.harvard.edu/hub_feeds/3661/feed_items/12124884/controls TagTeam :: Oxidative DNA damage promotes vascular aging associated with changes in extracellular... dna damage https://www.ncbi.nlm.nih.gov/protein/8FS4_F Chain F, DNA damage checkpoint control protein MEC3 - Protein - NCBI dna damage chain f checkpoint control https://www.frontiersin.org/journals/oncology/articles/10.3389/fonc.2012.00029/full Frontiers | CRL Ubiquitin Ligases and DNA Damage Response Cullin/RING ubiquitin ligases (CRL) comprise the largest subfamily of ubiquitin ligases and are involved in various biological processes. One of the main fun... ubiquitin ligases dna damage frontiers crl response https://cordis.europa.eu/project/id/660220/results Characterization and implications of DNA damage response in liver cancer | EpiLIVER | Project |... Deliverables, publications, datasets, software, exploitable results dna damage response https://research.wur.nl/en/publications/p21-ablation-in-liver-enhances-dna-damage-cholestasis-and-carcino/ p21 Ablation in Liver Enhances DNA Damage, Cholestasis, and Carcinogenesis - Wageningen University... dna damage https://pmc.ncbi.nlm.nih.gov/articles/PMC108832/ The Saccharomyces cerevisiae RAD9 Checkpoint Reduces the DNA Damage-Associated Stimulation of... Genetic instability in the Saccharomyces cerevisiae rad9 mutant correlates with failure to arrest the cell cycle in response to DNA damage. We quantitated the... saccharomyces cerevisiae dna damage checkpoint https://researchconnect.buffalo.edu/en/publications/hematological-cardiovascular-and-oxidative-dna-damage-markers-ass/ Hematological, cardiovascular and oxidative DNA damage markers associated with heavy metal exposure... dna damage https://www.frontiersin.org/research-topics/69728/role-of-dna-damage-repair-in-thoracic-cancers Frontiers | Role of DNA Damage Repair in Thoracic Cancers Lung cancer, a leading cause of cancer-related deaths globally, is characterized by significant genomic instability, which is a hallmark of various cancers. ... dna damage repair frontiers role thoracic cancers https://www.mdpi.com/1422-0067/24/5/4920 The Cellular Response to Complex DNA Damage Induced by Ionising Radiation Radiotherapy (ionising radiation; IR) is utilised in the treatment of ~50% of all human cancers, and where the therapeutic effect is largely achieved through... dna damage cellular response complex https://pubmed.ncbi.nlm.nih.gov/12760031/ DNA damage recognition and nucleotide excision repair in mammalian cells DNA damage recognition and nucleotide excision repair in mammalian cells dna damage recognition nucleotide excision repair https://pubmed.ncbi.nlm.nih.gov/21295155/ Mononuclear leukocyte DNA damage and oxidative stress: the association with smoking of hand-rolled... Cigarette smoking is a major cause of human cancer at various sites, although its carcinogenic mechanisms still remain unestablished. Based on the use of a... https://pmc.ncbi.nlm.nih.gov/articles/PMC5856454/ Pharmacologic ascorbate induces neuroblastoma cell death by hydrogen peroxide mediated DNA damage... An ascorbate-mediated production of oxidative stress has been shown to retard tumor growth. Subsequent glycolysis inhibition has been suggested. Here, we... cell death https://pubmed.ncbi.nlm.nih.gov/16275785/ DNA damage and replication stress induced transcription of RNR genes is dependent on the Ccr4-Not... Genetic experiments have indicated a role for the Ccr4-Not complex in the response to hydroxyurea (HU) induced replication stress and ionizing radiation in... https://journals.plos.org/plosgenetics/article?id=10.1371/journal.pgen.1009302 UV-exposure, endogenous DNA damage, and DNA replication errors shape the spectra of genome changes... Author summary Skin forms the first barrier against a variety of environmental toxins and DNA damaging agents. Additionally, DNA of skin cells suffer from... https://pubmed.ncbi.nlm.nih.gov/27711223/ The Bacterial Mfd Protein Prevents DNA Damage Induced by the Host Nitrogen Immune Response in a... Production of reactive nitrogen species is an important component of the host immune defence against bacteria. Here, we show that the bacterial protein Mfd...