https://www.iasp-pain.org/publications/pain-research-forum/papers-of-the-week/paper/novel-expression-of-major-histocompatibility-complex-ii-in-dorsal-root-ganglion-neurons-attenuates-paclitaxel-induced-cold-hypersensitivity-in-male-and-female-mice/
Chemotherapy is often a life-saving cancer treatment, but the development of intractable pain caused by chemotherapy-induced peripheral neuropathy (CIPN) is a...
complex iidorsal rootnovelexpressionmajor
https://pubmed.ncbi.nlm.nih.gov/11160499/?dopt=Abstract
The spontaneous, ectopic activity in sensory nerves that is induced by peripheral nerve injury is thought to contribute to the generation of "neuropathic" pain...
axotomyautotomyinducedchangesrat
https://www.iasp-pain.org/publications/pain-research-forum/papers-of-the-week/paper/202848-rna-profiling-human-dorsal-root-ganglia-reveals-sex-differences-mechanisms-promoting/
Neuropathic pain is a leading cause of high impact pain, is often disabling and is poorly managed by current therapeutics. Here we focused on a unique group of...
dorsal root gangliasex differencesrnaprofilinghuman
https://www.frontiersin.org/journals/pain-research/articles/10.3389/fpain.2022.948689/full
Peripheral nerve injury (PNI) induces neuronal hyperexcitability, which underlies neuropathic pain. The emergence of RNA sequencing technologies has enabled ...
fatty acid metabolismdorsal rootfrontiersprofiling
https://www.preprints.org/manuscript/202404.1986
Glutamate functions as the major excitatory neurotransmitter for primary sensory neurons and has a crucial role in sensitizing peripheral nociceptor terminals...
nerve growth factorsignalingexpressionglutaminase
https://www.iasp-pain.org/publications/pain-research-forum/papers-of-the-week/paper/132489-quantitative-characterization-neuropeptide-level-changes-dorsal-horn-and-dorsal-root/
Chronic itch can be extremely devastating and, in many cases, difficult to treat. One challenge in treating itch disorders is the limited understanding of the...
dorsal hornquantitativecharacterizationneuropeptidelevel