https://www.sigmaaldrich.com/CL/en/technical-documents/technical-article/cell-culture-and-cell-culture-analysis/cell-counting-and-health-analysis/caco-2-model
Caco-2 Intestinal Drug Transporter Models for More Predictive Drug Absorption
Utilize these Caco-2 cell based assay tools for screening small molecule drug compounds prior to clinical studies and submission to regulatory agencies.
caco 2drug transporterfor moreintestinalmodels
https://pmc.ncbi.nlm.nih.gov/articles/PMC8338929/
Acetylation turns leucine into a drug by membrane transporter switching - PMC
Small changes to molecules can have profound effects on their pharmacological activity as exemplified by the addition of the two-carbon acetyl group to make...
a drugmembrane transporteracetylationturnsleucine
https://www.jci.org/articles/view/76207/citations
JCI - Citations to A2A adenosine receptor modulates drug efflux transporter P-glycoprotein at the...
https://www.frontiersin.org/journals/immunology/articles/10.3389/fimmu.2025.1511029/full
Frontiers | Discovery of drug transporter inhibitors tied to long noncoding RNA in resistant cancer...
Chemotherapeutic resistance is a major obstacle to chemotherapeutic failure. Cancer cell resistance involves several mechanisms, including epithelial-to-mese...
https://www.jci.org/articles/view/76207/figure/1
JCI - A2A adenosine receptor modulates drug efflux transporter P-glycoprotein at the blood-brain...