https://digitalcommons.wayne.edu/oa_theses/132/
"Novel inhibitors of lysine specific demethylase 1 as epigenetic modulators " by Michael Crowley
The recently discovered enzyme lysine-specific demethylase 1 (LSD1) plays an important role in the epigenetic control of gene expression, and aberrant gene...
epigenetic modulatorsmichael crowleynovelinhibitorslysine
https://www.preprints.org/manuscript/202407.0980
A Benefaction of Flavonoids as Epigenetic Modulators for Effective Cancer Treatment[v1] |...
Histone changes that are adjustable and transmitted without altering the DNA sequence are part of epigenetic control. In many disorders, most famously...
epigenetic modulatorscancer treatmentbenefactionflavonoidseffective
https://db.cngb.org/data_resources/project/PRJNA871250
Multi-Omics Biomarkers of Response to Immunotherapy in Combination with Epigenetic Modulators -...
Epigenetic immunomodulation by association of guadecitabine with ipilimumab (NIBIT-M4 Phase Ib trial, NCT02608437) has been shown to be safe and tolerable in...
epigenetic modulatorsmultiomicsbiomarkersresponse
https://cordis.europa.eu/project/id/101062363/es
Development of dual-targeting epigenetic modulators for polypharmacology-based cancer therapy |...
Cancer is a multifactorial disorder involving different genetic and epigenetic alterations. Since epigenetic modifications are brought about by multiple...
epigenetic modulatorscancer therapydevelopmentdualtargeting