Robuta

https://elifesciences.org/articles/10365 Unravelling druggable signalling networks that control F508del-CFTR proteostasis | eLife Analysis of the mechanism of action of cystic fibrosis corrector drugs reveals signalling pathways potently controlling the proteostasis of the main... f508del cftrunravellingdruggablesignallingnetworks https://www.frontiersin.org/journals/pharmacology/articles/10.3389/fphar.2011.00048/full Frontiers | Stimulation of Wild-Type, F508del- and G551D-CFTR Chloride Channels by Non-Toxic... Cystic Fibrosis is a major inherited disorder involving abnormalities of fluid and electrolyte transport in a number of different organs due to abnormal func...