https://www.stjude.org/research/why-st-jude/scientific-report/2024/gain-of-function-mutation-reveals-new-target-in-pediatric-acute-myeloid-leukemia.html
Gain-of-function mutation reveals new target in pediatric acute myeloid leukemia | St. Jude Research
St. Jude discovered a mutation in UBTF in acute myeloid leukemia (AML). Discover how the tandem duplication may lead to the discovery of novel vulnerabilities.
gain of function mutation
https://www.jci.org/articles/view/140615
JCI - Gain-of-function mutation in ubiquitin ligase KLHL24 causes desmin degradation and dilatation...
gain of function mutation