https://pubmed.ncbi.nlm.nih.gov/28964699/
Multiple regulatory regions have the potential to regulate a single gene, yet how these elements combine to affect gene expression remains unclear. To uncover...
gene regulationmultiplexenhancerinterferencereveals
https://pubmed.ncbi.nlm.nih.gov/19828706/
Children and adolescents with 1 or 2 FTO rs9939609 obesity-risk alleles report more frequent LOC eating episodes and select foods higher in fat at a buffet...
fto geneobesityriskalleleloss
https://www.joshtycko.com/publications/38906-tunable-self-contained-gene-dosage-control-via-proteolytic-cleavage-of-crispr-cas-systems
Abstract Gene therapy holds great therapeutic potential. Yet, controlling cargo expression in single cells is limited due to the variability of delivery me...
gene dosagejoshselfcontainedcontrol
https://elifesciences.org/articles/65654v1
Ubiquitous transcriptional factor-CBP/p300 interaction induces epigenetic and transcriptional bimodality, which can be utilized to tune mean gene expression...
gene expressionquantitativecontrolnoisemammalian