https://pmc.ncbi.nlm.nih.gov/articles/PMC4992665/
Genetic Screens to Study the Immune System in Cancer - PMC
RNA interference and CRISPR/Cas9 technologies now enable systematic discovery of genes that regulate key pathways in the complex interaction between immune...
the immune systemgenetic screensto studycancerpmc
https://pubmed.ncbi.nlm.nih.gov/41077127/
Genetic screens of imaging-derived kidney volumes identify genes linked to kidney function
GWAS for 9,803,932 common genetic variants identified 34 significant loci for TKV, 24 for medulla, 26 for cortex, and 71 for sinus, compared to 32 for eGFR....
genetic screens
https://pubmed.ncbi.nlm.nih.gov/32483332/
Targeted Perturb-seq enables genome-scale genetic screens in single cells
The transcriptome contains rich information on molecular, cellular and organismal phenotypes. However, experimental and statistical limitations constrain...
genetic screenstargetedseqgenome
https://ocw.mit.edu/courses/7-15-experimental-molecular-genetics-spring-2015/external-resources/the-art-and-design-of-genetic-screens-caenorhabditis-elegans_2df13eea-82da-4a8f-965b-6b451981fe48/
The Art and Design of Genetic Screens: *Caenorhabditis Elegans* | Experimental Molecular Genetics |...
MIT OpenCourseWare is a web based publication of virtually all MIT course content. OCW is open and available to the world and is a permanent MIT activity
art and designgenetic screens
https://pubmed.ncbi.nlm.nih.gov/21185377/
Genetic screens using the piggyBac transposon
Transposons are an attractive system to use in genetic screens as they are molecularly tractable and the disrupted loci that give rise to the desired phenotype...
genetic screensusing
https://scholars.duke.edu/publication/734126
Scholars@Duke publication: Drosophila, genetic screens, and cardiac function.
genetic screensscholarsdukepublicationdrosophila
https://pubmed.ncbi.nlm.nih.gov/34018332/
A method for benchmarking genetic screens reveals a predominant mitochondrial bias
We present FLEX (Functional evaluation of experimental perturbations), a pipeline that leverages several functional annotation resources to establish reference...
genetic screensmethodbenchmarkingrevealsmitochondrial
https://journals.plos.org/plosgenetics/article?id=10.1371/journal.pgen.1008336
Genetic screens reveal novel major and minor players in magnesium homeostasis of Staphylococcus...
Author summary Magnesium is the most abundant metal ion in cells, yet to grow they still need to maintain its concentration within acceptable parameters...
major and minor