https://www.mdpi.com/1422-0067/23/13/7286
Noncatalytic Domains in DNA Glycosylases
Many proteins consist of two or more structural domains: separate parts that have a defined structure and function. For example, in enzymes, the catalytic...
domainsdnaglycosylases
https://elifesciences.org/articles/49044
NEIL1 and NEIL2 DNA glycosylases protect neural crest development against mitochondrial oxidative...
NEIL DNA glycosylases are required to counteract oxidative base damages within the mitochondrial genome to safeguard neural crest cell differentiation.
dna glycosylases
https://pmc.ncbi.nlm.nih.gov/articles/PMC15025/
The alpha/beta fold uracil DNA glycosylases: a common origin with diverse fates - PMC
Uracil DNA glycosylases (UDGs) are major repair enzymes that protect DNA from mutational damage caused by uracil incorporated as a result of a polymerase error...
https://www.nist.gov/publications/enhancing-efficacy-cancer-therapy-use-small-molecule-inhibitors-dna-glycosylases
Enhancing the Efficacy of Cancer Therapy: Use of Small Molecule Inhibitors of DNA Glycosylases as...
Feb 19, 2020 - Chemotherapy aims to destroy cancer cells by damaging their DNA.