Robuta

https://pubmed.ncbi.nlm.nih.gov/38465473/ Polr3b heterozygosity in mice induces both beneficial and deleterious effects on health during... The genetic pathways that modulate ageing in multicellular organisms are typically highly conserved across wide evolutionary distances. Recently RNA polymerase... https://www.cirm.ca.gov/cirm-trial/solid-tumor-analysis-for-hla-loss-of-heterozygosity-loh-and-apheresis-for-car-t-cell-manufacturing/ Solid Tumor Analysis for HLA Loss of Heterozygosity (LOH) and Apheresis for CAR T- Cell... https://pubmed.ncbi.nlm.nih.gov/38899694/ APOE3 Christchurch Heterozygosity and Autosomal Dominant Alzheimer's Disease christchurchheterozygosityautosomaldominantalzheimer https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0043254 The Limits of Mean-Field Heterozygosity Estimates under Spatial Extension in Simulated Plant... Computational models of evolutionary processes are increasingly required to incorporate multiple and diverse sources of data. A popular feature to include in... https://www.mdpi.com/2073-4425/15/12/1542 Loss of Heterozygosity (LOH) Affecting HLA Genes in Breast Cancer: Clinical Relevance and... Major histocompatibility complex (MHC) class-I molecules (or Human Leucocyte Antigen class-I) play a key role in adaptive immunity against cancer. They present... https://pubmed.ncbi.nlm.nih.gov/41996162/ Extensive heterozygosity and genetic exchange among natural populations of Leishmania species extensiveheterozygositygeneticexchange https://researchconnect.buffalo.edu/en/publications/functional-loss-of-tumor-suppressor-genes-detected-by-loss-of-het/ Functional loss of tumor suppressor genes detected by loss of heterozygosity, but not driver... https://pubmed.ncbi.nlm.nih.gov/19933189/ Compound heterozygosity of two novel truncation mutations in RP1 causing autosomal recessive... Purpose. To evaluate the phenotypic effects of two novel frameshift mutations in the RP1 gene in a Chinese pedigree of autosomal recessive retinitis pigmentosa... https://experts.arizona.edu/en/publications/inferring-compound-heterozygosity-from-large-scale-exome-sequenci/ Inferring compound heterozygosity from large-scale exome sequencing data - University of Arizona large scale https://www.wikidata.org/wiki/Q36135600 Loss of heterozygosity on chromosome 5q in ovarian cancer is frequently accompanied by TP53... https://pubmed.ncbi.nlm.nih.gov/39401533/ A novel genetic mouse model of osteoporosis with double heterozygosity of Irx3 and Irx5... Iroquois homeobox gene 3 (Irx3) and Irx5 encode transcription factors that play crucial roles in limb development and bone formation. Previous studies using... https://portal.fis.tum.de/en/publications/loss-of-heterozygosity-in-the-hla-class-i-region-in-human-pancrea-2/ Loss of heterozygosity in the HLA class I region in human pancreatic cancer - Technical University... https://portal.fis.tum.de/en/publications/heterozygosity-for-il23r-parg381gln-confers-a-protective-effect-n/ Heterozygosity for IL23R p.Arg381Gln confers a protective effect not only against Crohn's disease... https://pmc.ncbi.nlm.nih.gov/articles/PMC12698500/ Familial Mediterranean Fever With Compound Heterozygosity for the Pyrin Variant L110P-E148Q: A Case... Familial Mediterranean fever (FMF) is a monogenic autoinflammatory disorder caused by MEFV mutations. Exon 10 variants such as M694V are high-penetrance... familial mediterranean fever https://pubmed.ncbi.nlm.nih.gov/20607612/ Transcobalamin deficiency caused by compound heterozygosity for two novel mutations in the TCN2... Transcobalamin (TC) deficiency (OMIM# 275350) is a rare, autosomal recessive disorder that presents in early infancy with a broad spectrum of symptoms,... https://cordis.europa.eu/project/id/310368 The role of loss-of-heterozygosity in cancer development and progression | DELCANCER | Project |... Somatically acquired loss-of-heterozygosity (LOH) is extremely common in cancer; deletions of recessive cancer genes, miRNAs, and regulatory elements, can... the role https://pure.psu.edu/en/publications/soft-selection-reduces-loss-of-heterozygosity-in-asexual-reproduc/ Soft selection reduces loss of heterozygosity in asexual reproduction - Penn State soft selectionasexual reproductionreducesloss https://www.techtransfer.nih.gov/patent/e-045-2022-0-ep-01 Method of HLA loss Heterozygosity Detection in Liquid Biopsies | Technology Transfer methodhlalossheterozygosity https://academiccommons.columbia.edu/doi/10.7916/D8C24TSW Mechanisms of increased risk of tumorigenesis in Atm and Brca1 double heterozygosity | Academic... Both epidemiological and experimental studies suggest that heterozygosity for a single gene is linked with tumorigenesis and heterozygosity for two genes... increased risk https://research-repository.uwa.edu.au/en/publications/loss-of-heterozygosity-on-chromosome-2q-possibly-a-poor-prognosti/ Loss of heterozygosity on chromosome 2q: Possibly a poor prognostic factor in head and neck cancer... https://scholars.uky.edu/en/publications/genetic-heterozygosity-and-gene-flow-in-coleomegilla-maculata-de-/ Genetic heterozygosity and gene flow in Coleomegilla maculata de geer (coleoptera: Coccinellidae) -... gene flow