https://www.frontiersin.org/journals/immunology/articles/10.3389/fimmu.2025.1722596/full
Frontiers | Enhancing functional antibody responses against HIV envelope V1V2 through vaccine...
BackgroundDespite decades of research, the development of an effective HIV vaccine remains a significant challenge. Recent findings from three large vaccine ...
functional antibodyhiv envelopefrontiersenhancingresponses
https://www.southampton.ac.uk/biosci/news/events/2020/02/26-inducing-neutralizing-antibodies.page?
Inducing neutralizing antibodies against HIV by native-like envelope trimers | Biological Sciences...
Find out more about the talk from Professor Rogier Sanders, within Biological Sciences at the University of Southampton.
neutralizing antibodies
https://pmc.ncbi.nlm.nih.gov/articles/PMC22722/
The ability of HIV type 1 to use CCR-3 as a coreceptor is controlled by envelope V1/V2 sequences...
Although infection by primary HIV type 1 (HIV-1) isolates normally requires the functional interaction of the viral envelope protein with both CD4 and the...
https://www.jci.org/articles/view/3273
JCI - HIV-1 envelope gp41 is a potent inhibitor of chemoattractant receptor expression and function...
https://www.uab.edu/medicine/news/featured-discovery/atomic-view-of-the-hiv-1-matrix-lattice
Atomic view of the HIV-1 matrix lattice. Implications on virus assembly and envelope incorporation...
https://www.rti.org/publication/hiv-1-envelope-gp41-antibodies-originate-terminal-ileum-b-cells-share-cross-reactivity-commensal-bac
HIV-1 envelope gp41 antibodies can originate from terminal ileum B cells that share...
Monoclonal antibodies derived from blood plasma cells of acute HIV-1-infected individuals are predominantly targeted to the HIV Env gp41 and cross-reactive...
https://www.rcsb.org/structure/2NY6
RCSB PDB - 2NY6: HIV-1 gp120 Envelope Glycoprotein (M95W, W96C, I109C, T123C, T257S, V275C,S334A,...
HIV-1 gp120 Envelope Glycoprotein (M95W, W96C, I109C, T123C, T257S, V275C,S334A, S375W, Q428C, G431C) Complexed with CD4 and Antibody 17b
https://www.rcsb.org/structure/5CAY
RCSB PDB - 5CAY: Envelope glycoprotein gp120 core from HIV type 2 bound to the first two domains of...
Envelope glycoprotein gp120 core from HIV type 2 bound to the first two domains of human soluble CD4 receptor
https://www.rti.org/publication/hiv-1-envelope-mimicry-host-enzyme-kynureninase-disrupt-tryptophan-metabolism
HIV-1 envelope mimicry of host enzyme kynureninase does not disrupt tryptophan metabolism | RTI
The HIV-1 envelope protein (Env) has evolved to subvert the host immune system, hindering viral control by the host. The tryptophan metabolic enzyme...
https://www.jci.org/articles/view/3273/pdf
JCI - HIV-1 envelope gp41 is a potent inhibitor of chemoattractant receptor expression and function...
https://pmc.ncbi.nlm.nih.gov/articles/PMC31878/
Localization of CD4+ T cell epitope hotspots to exposed strands of HIV envelope glycoprotein...
The spectrum of immunogenic epitopes presented by the H2-IAb MHC class II molecule to CD4+ T cells has been defined for two different (clade B and clade D) HIV...
cd4 t cell
https://www.ncbi.nlm.nih.gov/Structure/pdb/4RIR
4RIR: Structural Analysis of the Unmutated Ancestor of the HIV-1 Envelope V2 Region Antibody CH58...
CH58-UA Fab heavy chainCH58-UA Fab light chain
https://www.ktvu.com/news/lawyers-aetna-envelope-window-reveals-patients-hiv-status
Lawyers: Aetna envelope window reveals patients' HIV status | KTVU FOX 2
Health insurer Aetna reportedly exposed the personal data of HIV patients across the U.S. earlier this month when mailings to the patients revealed the...
window revealshiv statuslawyersaetnaenvelope
https://www.ncbi.nlm.nih.gov/Structure/pdb/6X9R
6X9R: HIV-1 Envelope Glycoprotein BG505 SOSIP.664 expressed in HEK293F cells in complex with RM20A3...
HIV-1 Envelope Glycoprotein BG505 SOSIP.664 gp120HIV-1 Envelope Glycoprotein BG505 SOSIP.664 gp41RM20A3 Fab Heavy ChainRM20A3 Fab Light...
https://www.mdpi.com/2076-393X/13/2/110
The Design and Immunogenicity of an HIV-1 Clade C Pediatric Envelope Glycoprotein Stabilized by...
Background: Elite-neutralizer-derived HIV-1 envelopes (Envs), which induce broadly neutralizing antibodies (bnAbs), can inform HIV-1 vaccine design by serving...
https://www.frontiersin.org/journals/immunology/articles/10.3389/fimmu.2020.01213/full
Frontiers | Harnessing Activin A Adjuvanticity to Promote Antibody Responses to BG505 HIV Envelope...
T follicular helper (TFH) cells are powerful regulators of affinity matured long-lived plasma cells. Eliciting protective, long-lasting antibody responses to...
activin a
https://elifesciences.org/articles/34420/figures
Figures and data in Mapping mutational effects along the evolutionary landscape of HIV envelope |...
Deep mutational scanning of Env proteins from two transmitted-founder strains of HIV shows how the accessible evolutionary space changes as the virus evolves.
https://elifesciences.org/articles/34420/peer-reviews
Peer review in Mapping mutational effects along the evolutionary landscape of HIV envelope | eLife
Deep mutational scanning of Env proteins from two transmitted-founder strains of HIV shows how the accessible evolutionary space changes as the virus evolves.
https://www.mdpi.com/2076-393X/9/7/750
Stepwise Conformational Stabilization of a HIV-1 Clade C Consensus Envelope Trimer Immunogen...
Stabilization of the HIV-1 Envelope glycoprotein trimer (Env) in its native pre-fusion closed conformation is regarded as one of several requirements for the...
https://elifesciences.org/reviewed-preprints/110354
HIV-1 Envelope glycoprotein modulates CXCR4 clustering and dynamics on the T cell membrane
https://pmc.ncbi.nlm.nih.gov/articles/PMC11209363/
Applying Flow Virometry to Study the HIV Envelope Glycoprotein and Differences Across HIV Model...
The HIV envelope glycoprotein (Env) is a trimeric protein that facilitates viral binding and fusion with target cells. As the sole viral protein on the HIV...
https://www.mdpi.com/1999-4915/12/2/241
Identification of HIV-1 Envelope Mutations that Enhance Entry Using Macaque CD4 and CCR5
Although Rhesus macaques are an important animal model for HIV-1 vaccine development research, most transmitted HIV-1 strains replicate poorly in macaque...