https://pubmed.ncbi.nlm.nih.gov/19726199/
By targeting multi-active sites of acetylcholinesterase (AChE), a series of huperzine A (Hup A) derivatives with various aromatic ring groups were designed and...
rational designsynthesishighlypotentanti
https://pubmed.ncbi.nlm.nih.gov/30989926/
To evaluate the efficacy and safety of huperzine in treating patients with mild cognitive impairment. The randomized controlled trials(RCT) were retrieved from...
efficacysafetyhuperzinetreatingpatients
https://pubmed.ncbi.nlm.nih.gov/17056129/
In recent years, the most common pharmacological treatment for Alzheimer's disease (AD) has been acetylcholinesterase (AChE) inhibition. However, this...
neuroprotectiveeffectshuperzinenewtherapeutic
https://pubmed.ncbi.nlm.nih.gov/16220957/
The entering and leaving processes of Huperzine A (HupA) binding with the long active-site gorge of Torpedo californica acetylcholinesterase (TcAChE) have been...
huperzineenterleavebindinggorge