Robuta

https://pmc.ncbi.nlm.nih.gov/articles/PMC21723/ BCL-6 mutations in normal germinal center B cells: Evidence of somatic hypermutation acting outside... The molecular mechanism involved in the process of antigen-driven somatic hypermutation of Ig genes is unknown, but it is commonly believed that this mechanism... https://www.osti.gov/pages/biblio/1617746-mobile-element-muts-drives-hypermutation-marine-vibrio A Mobile Element in mutS Drives Hypermutation in a Marine Vibrio (Journal Article) | OSTI.GOV The U.S. Department of Energy's Office of Scientific and Technical Information https://www.wikidata.org/wiki/Q37675025 Hypermutation at the immunoglobulin heavy chain locus in a pre-B-cell line - Wikidata scientific article published on January 1985 https://pmc.ncbi.nlm.nih.gov/articles/PMC21155/ Both DNA strands of antibody genes are hypermutation targets - PMC During the maturation of the immune response, antibody genes are subjected to localized hypermutation. Mutations are not evenly distributed along the V gene;... dnastrandsantibodygeneshypermutation https://pmc.ncbi.nlm.nih.gov/articles/PMC19480/ Modifying the sequence of an immunoglobulin V-gene alters the resulting pattern of hypermutation -... Affinity maturation of antibodies requires localized hypermutation and antigen selection. Hypermutation is particularly active in certain regions (notably the... the sequence https://www.frontiersin.org/journals/immunology/articles/10.3389/fimmu.2024.1505896/full Frontiers | Association between somatic microsatellite instability, hypermutation status, and... BackgroundMicrosatellite instability-high (MSI-high) tumors comprise ~15% of sporadic colorectal cancers (CRC) and are associated with elevated T cell infilt... microsatellite instabilityfrontiersassociationsomatichypermutation https://elifesciences.org/reviewed-preprints/87607/reviews Long-read single-cell sequencing reveals expressions of hypermutation clusters of isoforms in human... single cell sequencing