https://www.jci.org/articles/view/159806
JCI - GIGYF1 disruption associates with autism and impaired IGF-1R signaling
igf 1rjcidisruptionassociates
https://www.rcsb.org/structure/3NW6
RCSB PDB - 3NW6: Crystal structure of insulin-like growth factor 1 receptor (IGF-1R-WT) complex...
Crystal structure of insulin-like growth factor 1 receptor (IGF-1R-WT) complex with a carbon-linked proline isostere inhibitor (11A)
insulin like growth factor 1
https://pmc.ncbi.nlm.nih.gov/articles/PMC7078196/
Lipoic acid decreases breast cancer cell proliferation by inhibiting IGF-1R via furin...
Breast cancer is the second most common cancer in the world. Despite advances in therapies, the mechanisms of resistance remain the underlying cause of...
https://www.biospace.com/innovent-announces-first-participant-dosed-in-phase-2-study-of-ibi311-anti-igf-1r-monoclonal-antibody-in-patients-with-thyroid-associated-ophthalmopathy
Innovent Announces First Participant Dosed in Phase 2 Study of IBI311 (Anti-IGF-1R Monoclonal...
Feb 15, 2023 - Innovent Biologics, Inc. announces that the first patient with thyroid associated ophthalmopathy has been successfully dosed in the Phase 2 study of IBI311, a...