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https://medlineplus.gov/lab-tests/csf-immunoglobulin-g-igg-index/ CSF Immunoglobulin G (IgG) Index: MedlinePlus Medical Test A CSF IgG index measures the level of some antibodies in your cerebrospinal fluid. It is used to help check for multiple sclerosis. Learn more. immunoglobulin gigg indexcsfmedlineplusmedical