immunotoxin - Robuta Search

https://pubmed.ncbi.nlm.nih.gov/39561285/ Bivalent CD47 immunotoxin for targeted therapy of T-cell acute lymphoblastic leukemia CD47 is overexpressed on the surface of many types of cancer cells, including T-cell acute lymphoblastic leukemia (T-ALL) cells. In this study, we have... targeted therapy https://www.techtransfer.nih.gov/patent/e-117-2011-0-ru-16 Recombinant Immunotoxin Targeting Mesothelin | Technology Transfer recombinant targeting mesothelin technology transfer https://pubmed.ncbi.nlm.nih.gov/7708720/ Intrathecal administration of single-chain immunotoxin, LMB-7 [B3(Fv)-PE38], produces cures of... LMB-7 [B3(Fv)-PE38] is a single-chain immunotoxin constructed from the murine monoclonal antibody B3 and a truncated from of Pseudomonas exotoxin PE38.... https://www.techtransfer.nih.gov/patent/e-117-2011-0-ma-32 Recombinant Immunotoxin Targeting Mesothelin | Technology Transfer recombinant targeting mesothelin technology transfer https://pubmed.ncbi.nlm.nih.gov/7519937/ XomaZyme-CD5 immunotoxin in conjunction with partial T cell depletion for prevention of graft... Patients who receive bone marrow transplants from unrelated donors have a high incidence of graft-versus-host disease (GVHD). If the donor marrow is first T... https://www.techtransfer.nih.gov/patent/e-046-2004-0-us-03 Improvements To BL22 Immunotoxin | Technology Transfer improvements technology transfer https://pubmed.ncbi.nlm.nih.gov/24989332/ Phase 1 study of the antimesothelin immunotoxin SS1P in combination with pemetrexed and cisplatin... SS1P given with pemetrexed and cisplatin is safe and well tolerated and exhibits significant antitumor activity in patients with unresectable, advanced pleural... https://scholarworks.indianapolis.iu.edu/items/414fea48-7165-42ed-b188-cc5a5f8c17f7 Immunotoxin SS1P is rapidly removed by proximal tubule cells of kidney, whose damage contributes to... Recombinant immunotoxins (RITs) are chimeric proteins composed of an Fv and a protein toxin being developed for cancer treatment. The Fv brings the toxin to... https://www.cancer.gov/publications/dictionaries/cancer-drug/def/anti-cd3-cd7-ricin-toxin-a-immunotoxin Definition of anti-CD3/CD7-ricin toxin A immunotoxin - NCI Drug Dictionary - NCI Find technical definitions and synonyms by letter for drugs/agents used to treat patients with cancer or conditions related to cancer. Each entry includes... definition of https://www.techtransfer.nih.gov/patent/e-201-1998-0-au-03 SPECIFIC KILLING OF HIV-INFECTED LYMPHOCYTES BY A RECOMBINANT IMMUNOTOXIN DIRECTED AGAINST THE... https://www.frontiersin.org/journals/microbiology/articles/10.3389/fmicb.2025.1603671/full Frontiers | Unlocking the potential of engineered microbes in immunotoxin-based cancer therapy Immunotoxins (ITs), as targeted cancer therapies, confront limitations including off-target effects, immunogenicity, and inadequate tumor penetration, hinder... the potential https://www.cancer.gov/publications/dictionaries/cancer-drug/def/anti-b4-blocked-ricin-immunotoxin Definition of anti-B4 blocked ricin immunotoxin - NCI Drug Dictionary - NCI Find technical definitions and synonyms by letter for drugs/agents used to treat patients with cancer or conditions related to cancer. Each entry includes... definition of anti blocked ricin nci https://pubmed.ncbi.nlm.nih.gov/20445347/ Anti-melanoma activity of the 9.2.27PE immunotoxin in dacarbazine resistant cells We have earlier shown that the 9.2.27 Pseudomonas Exotoxin A (PE) immunotoxin (IT) efficiently kills melanoma cells through inhibition of protein synthesis... https://www.techtransfer.nih.gov/patent/e-117-2011-0-br-04 Recombinant Immunotoxin Targeting Mesothelin | Technology Transfer recombinant targeting mesothelin technology transfer https://www.techtransfer.nih.gov/patent/e-163-1993-2-lu-18 IMMUNOTOXIN CONTAINING A DISULFIDE-STABILIZED ANTIBODY FRAGMENT JOINED TO A PSEUDOMONAS EXOTOXIN... containing disulfide stabilized https://pubchem.ncbi.nlm.nih.gov/patent/EP-0130132-A1 Antitumour immunotoxin, pharmaceutical compositions containing it, and its use in vitro - Patent... EP-0130132-A1 chemical patent summary. https://www.techtransfer.nih.gov/patent/e-121-2005-0-pct-02 Polymer-linked Pseudomonas Exotoxin Immunotoxin | Technology Transfer polymer linked pseudomonas technology transfer https://www.techtransfer.nih.gov/patent/e-079-2020-2-pct-01 IMMUNOTHERAPY WITH COMBINATION THERAPY COMPRISING AN IMMUNOTOXIN | Technology Transfer combination therapy immunotherapy technology transfer https://www.techtransfer.nih.gov/patent/e-163-1993-2-de-13 IMMUNOTOXIN CONTAINING A DISULFIDE-STABILIZED ANTIBODY FRAGMENT JOINED TO A PSEUDOMONAS EXOTOXIN... containing disulfide stabilized https://www.techtransfer.nih.gov/patent/e-268-2007-0-us-06 FOLD-BACK DIABODY DIPHTHERIA TOXIN IMMUNOTOXIN AND METHODS OF USE | Technology Transfer methods of use https://www.techtransfer.nih.gov/patent/e-044-1997-1-gb-11 Immunotoxin Fusion Proteins And Means For Expression Thereof | Technology Transfer fusion proteins means expression technology transfer https://www.techtransfer.nih.gov/patent/e-440-1987-0-us-01 COMPOSITIONS AND METHODS FOR IMMUNOTOXIN THERAPY TO CARCINOMA CELLS | Technology Transfer compositions methods