integrase - Robuta Search

https://elifesciences.org/articles/46344

HIV-1 integrase tetramers are the antiviral target of pyridine-based allosteric integrase...

Pyridine-based allosteric inhibitors selectively target HIV-1 integrase tetramers and exhibit enhanced antiviral activity against a dolutegravir resistant...

hiv integrase tetramers antiviral target

https://www.rcsb.org/structure/3HPG

RCSB PDB - 3HPG: Visna virus integrase (residues 1-219) in complex with LEDGF IBD: examples of open...

Visna virus integrase (residues 1-219) in complex with LEDGF IBD: examples of open integrase dimer-dimer interfaces

visna virus rcsb pdb integrase residues

https://www.ncbi.nlm.nih.gov/Structure/pdb/3UXU

3UXU: The structure of the catalytic domain of the Sulfolobus Spindle-shaped viral integrase...

Probable integrasePHOSPHATE ION

catalytic domain structure sulfolobus

https://www.ncbi.nlm.nih.gov/Structure/pdb/6EN0

6EN0: Structure of the Tn1549 transposon Integrase (aa 82-397) in complex with circular...

DNA (44-MER)Int protein

structure transposon integrase aa

https://www.mdpi.com/2076-0817/13/2/102

Comprehensive Analysis of HIV-1 Integrase Resistance-Related Mutations in African Countries

The growing emergence of non-nucleoside reverse transcriptase inhibitor (NNRTI) HIV drug resistance in sub-Saharan Africa (SSA) led to the World Health...

comprehensive analysis hiv integrase resistance

https://www.ncbi.nlm.nih.gov/Structure/pdb/3L3U

3L3U: Crystal structure of the HIV-1 integrase core domain to 1.4A

POL polyproteinSULFATE ION

crystal structure the hiv integrase core domain